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XL228
go.drugbank.com/drugs/DB05184InvestigationalXL228 is a novel anticancer compound designed to inhibit the insulin-like growth factor type-1 receptor (IGF1R), Src and Abl tyrosine kinases – targets that play crucial roles in cancer cell proliferation
Mus musculus skin
go.drugbank.com/drugs/DB10412ApprovedMus musculus skin or pelt is used in allergenic testing.
Categories: Non-Standardized Animal Skin Allergenic ExtractCavia porcellus skin
go.drugbank.com/drugs/DB10416ApprovedCavia porcellus skin or pelt is used in allergenic testing.
Categories: Non-Standardized Animal Skin Allergenic ExtractMeriones unguiculatus skin
go.drugbank.com/drugs/DB10603ApprovedMeriones unguiculatus skin or pelt is used in allergenic testing.
Categories: Non-Standardized Animal Skin Allergenic ExtractCapra hircus skin
go.drugbank.com/drugs/DB10604ApprovedCapra hircus skin or pelt is used in allergenic testing.
Categories: Non-Standardized Animal Skin Allergenic ExtractOryctolagus cuniculus skin
go.drugbank.com/drugs/DB10607ApprovedOryctolagus cuniculus skin or pelt is used in allergenic testing.
Categories: Non-Standardized Animal Skin Allergenic ExtractRilapladib
go.drugbank.com/drugs/DB05119InvestigationalRilapladib is the third genomics-derived small molecule drug arising from the Human Genome Sciences-GlaxoSmithKline collaboration to enter clinical development. … It is a lipoprotein-associated phospholipase A2 (Lp-PLA2) inhibitor. Lp-PLA2 is an enzyme associated with the formation of atherosclerotic plaques.
Pazopanib
go.drugbank.com/drugs/DB06589ApprovedInvestigationalPazopanib is a small molecule inhibitor of multiple protein tyrosine kinases with potential antineoplastic activity. It is developed by GlaxoSmithKline and was FDA approved on October 19, 2009.
IL-2 pDNA
go.drugbank.com/drugs/DB05935ExperimentalVical incorporated has initiated a human Phase 1 study of an investigational method of delivering interleukin-2 (IL-2), a potent immune system stimulant, for patients with recurrent metastatic melanoma
Synonyms: IL-2 pDNAXMT-1001
go.drugbank.com/drugs/DB06069InvestigationalXMT-1001 has demonstrated an improved therapeutic window as compared with CPT and irinotecan in human tumor xenografts models … In this novel CPT pro-drug, CPT is conjugated with a 70 kDa biodegradable hydrophilic polyacetal, poly (1-hydroxymethylene hydroxylmethylformal).
Categories: Compounds used in a research, industrial, or household setting