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Displaying results 4761 - 4770 of 10000 in total
  1. Drug

    MLN0415

    go.drugbank.com/drugs/DB05183
    Experimental

    Because inflammatory proteins play a critical role in inflammation and drive the inflammatory response to disease, controlling these proteins may prevent or slow disease progression. … In preclinical studies, MLN0415 was shown to decrease NF-kB activation and down-regulate the expression of a number of inflammatory proteins.

  2. Drug

    Benzododecinium

    go.drugbank.com/drugs/DB13282
    Investigational

    Benzododecinium is used as an antiseptic/disinfectant compound. It has been marketed as a tincture for antiseptic product for wounds in the Czech Republic.

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Contezolid

    go.drugbank.com/drugs/DB12796
    Investigational

    MRX-I has been used in trials studying the treatment of Bacterial Infections.

    Synonyms: MRX-ICategories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  4. Drug

    ATG-Fresenius S

    go.drugbank.com/drugs/DB05320
    Investigational

    ATG-Fresenius S is an immunosuppressive product for the prevention and treatment of acute rejection following organ transplantation. … ATG-Fresenius S is a concentrated anti-human T-lymphocyte immunoglobulin preparation derived from rabbits after immunization with a T-lympoblast cell line.

  5. Drug

    Lobeline

    go.drugbank.com/drugs/DB05137
    Investigational

    It has been proposed for a variety of therapeutic uses including in respiratory disorders, peripheral vascular disorders, insomnia, and smoking cessation. [PubChem] … An alkaloid that has actions similar to nicotine on nicotinic cholinergic receptors but is less potent.

  6. Drug

    Sorghum halepense pollen

    go.drugbank.com/drugs/DB10365
    Approved

    Sorghum halepense pollen is the pollen of the Sorghum halepense plant. Sorghum halepense pollen is mainly used in allergenic testing.

    Mixtures: Mixture of Standardized and Non-Standardized Southern Grasses, Mixture of Twenty-Two Standardized and Non-Standardized GrassesCategories: Non-Standardized Pollen Allergenic Extract
  7. Drug

    Droloxifene

    go.drugbank.com/drugs/DB15641
    Experimental

    It may have a particular role in situations in which rapid pharmacokinetics, or an increased antiestrogenic to estrogenic ratio, are required. … Droloxifene has an anti-implantation effect in rats, and the effect appears to be not completely due to its anti-estrogenic activity.[L34184]

    Categories: Compounds used in a research, industrial, or household setting
  8. Drug

    Asfotase alfa

    go.drugbank.com/drugs/DB09105
    ApprovedInvestigational

    Asfotase alfa is a first-in-class bone-targeted enzyme replacement therapy designed to address the underlying cause of hypophosphatasia (HPP)—deficient alkaline phosphatase (ALP). … Food and Drug Administration (FDA) on October 23, 2015. Asfotase Alfa is marketed under the brand name Strensiq® by Alexion Pharmaceuticals, Inc.

  9. Drug

    Mirodenafil

    go.drugbank.com/drugs/DB11792
    Investigational

    Mirodenafil has been used in trials studying the treatment and supportive care of Kidney Diseases, Urologic Diseases, Renal Insufficiency, Erectile Dysfunction, and Male Erectile Dysfunction.

  10. Drug

    Mapatumumab

    go.drugbank.com/drugs/DB18945
    Investigational

    Mapatumumab is under investigation in clinical trial NCT00094848 (Study of TRM-1 (TRAIL-R1 Monoclonal Antibody) in Subjects With Relapsed or Refractory Non-hodgkin's Lymphoma (NHL)).

    Synonyms: Trail-r 1mab, TRAIL-R1 mAb