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Displaying results 4791 - 4800 of 8700 in total
  1. Drug

    Isoaminile

    go.drugbank.com/drugs/DB08944
    ApprovedWithdrawn

    Isoaminile, an antitussive drug with a structure similar to methadone, is also an anticholinergic with both antimuscarinic and antinicotinic properties.

  2. Drug

    COVID19 s-vax loaded autologous dendritic cell vaccine

    go.drugbank.com/drugs/DB15814
    Experimental

    As of May 2020, the company is pursuing a human clinical trial (ChiCTR2000033003) to test the safety and immunogenicity of the vaccine. … DC-based vaccines are currently used in cancer therapeutics, and are being tested for COVID-19.

  3. Drug

    Norflurane

    go.drugbank.com/drugs/DB13116
    ApprovedInvestigationalWithdrawn

    Norflurane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).

    Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2E1 Substrates
  4. Drug

    Indopan

    go.drugbank.com/drugs/DB01446
    ExperimentalIllicit

    It was developed in the 1960's by Upjohn with the intention for use as an antidepressant. In the 1990's, indopan became regulated as a Schedule I controlled substance in the United states.

    Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates
  5. Drug

    Crinecerfont

    go.drugbank.com/drugs/DB18518
    ApprovedInvestigational

    [L51973] When administered alongside glucocorticoid replacement in patients with CAH it allows for the use of lower, physiological doses for glucocorticoid replacement, thereby reducing the risks associated … [A264818] Crinecerfont was approved by the FDA in December 2024 as an adjunct to glucocorticoid replacement in patients with CAH.[L51973,L51993]

    Categories: Corticotropin-releasing Factor Type 1 Receptor Antagonist, Cytochrome P-450 Substrates
  6. Drug

    Sulfaquinoxaline

    go.drugbank.com/drugs/DB11464
    ExperimentalVet approved

    Sulfaquinoxaline is a veterinary medicine which can be given to cattle and sheep to treat coccidiosis.It is available in Pakistan with Sanna Laboratories in combination with Amprolium and Vitamin K as

    Mixtures: Rhobazin Plus Solution for Oral Use
  7. Drug

    CY301

    go.drugbank.com/drugs/DB06382
    Experimental

    CY301 (Simplivir) is an investigational gene silencing compound developed by CytoGenix for the treatment of HSV.

  8. Drug

    AdPEDF

    go.drugbank.com/drugs/DB05138
    Experimental

    AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD).

  9. Drug

    Pradefovir mesylate

    go.drugbank.com/drugs/DB05478
    Investigational

    Pradefovir is undergoing phase II development for the treatment of chronic hepatitis B. … Pradefovir is activated through oxidation that is mediated by cytochrome P-450 (CYP) 3A4, which is predominantly expressed in the liver.

  10. Drug

    Pentafluoropropane

    go.drugbank.com/drugs/DB13117
    ApprovedWithdrawn

    Pentafluoropropane is under investigation in clinical trial NCT01673061 (Vapocoolant Spray for Numbing Small Boils Before Incision and Drainage).