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Inclisiran
go.drugbank.com/drugs/DB14901ApprovedInvestigationalis a major known risk factor for CVD. … Inclisiran is a long-acting, synthetic small interfering RNA (siRNA) directed against proprotein convertase subtilisin-kexin type 9 (PCSK9), which is a serine protease that regulates plasma low-density
Categories: Compounds used in a research, industrial, or household setting, Proprotein Convertase Subtilisin Kexin Type 9 (PCSK9) InhibitorsProducts: LYPTİMZİA 284 MG/1,5 ML ENJEKSİYONLUK ÇÖZELTİ İÇEREN KULLANIMA HAZIR ENJEKTÖR, 1 ADET, LEQVIO SOLUTION FOR INJECTION IN PREFILLED SYRINGE 284 MG/1.5 MLTestosterone enanthate
go.drugbank.com/drugs/DB13944ApprovedInvestigationalTestosterone enanthate is an esterified variant of testosterone that comes as an injectable compound with a slow-release rate. … s Xyosted - a subcutaneous testosterone enanthate product for once-weekly, at-home self-administration with an easy-to-use, single dose, disposable autoinjector [L4659].
Mixtures: NOFERTYL® INYECTABLECategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesFerric derisomaltose
go.drugbank.com/drugs/DB15617ApprovedInvestigational[A190528] Ferric derisomaltose is a form of iron used in the treatment of iron deficiency. This drug is a complex of iron (III) hydroxide and derisomaltose. … The latter is an iron carbohydrate oligosaccharide that works to release iron. Ferric derisomaltose was developed by Pharmacosmos Therapeutics ad was granted FDA approval in January 2020.
Products: MONOFER® SOLUTION FOR INJECTION OR INFUSION 100 MG/ML, Monofer 100 mg/ml solution for injection/infusion in vialsRopivacaine
go.drugbank.com/drugs/DB00296ApprovedInvestigationalIt exists as a racemate of its S- and R-enantiomers, although the marketed form is supplied only as the purified S-enantiomer.[L42140] … Ropivacaine is an aminoamide local anesthetic drug marketed by AstraZeneca under the trade name Naropin.
Synonyms: L-N-n-propylpipecolic acid-2,6-xylidide, (S)-(−)-1-propyl-2',6'-pipecoloxylidideCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesTrihexyphenidyl
go.drugbank.com/drugs/DB00376ApprovedInvestigational[A229103] Trihexyphenidyl is rarely used in the treatment of parkinsonism, and is not a first line treatment due to significant adverse effects. … [L31773,L31778] Its discovery was published in 1949 in a study looking for drugs with antispasmodic activity.
International brands: Ea TenCategories: Heterocyclic Compounds, 1-RingMivacurium
go.drugbank.com/drugs/DB01226ApprovedWithdrawnIt binds competitively to cholinergic receptors on the motor end-plate to antagonize the action of acetylcholine, resulting in a block of neuromuscular transmission. … Mivacurium is a bisbenzylisoquinolinium based neuromuscular blocker or muscle relaxant.
Categories: Heterocyclic Compounds, 2-RingProducts: MİVACRON 10 MG/5 ML ENJEKSİYONLUK ÇÖZELTİ, 5 ADET, MIVACRON INJECTION 10 mg/5 mlDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalIn September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension occurring in infants and neonates. … Diazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels.
Synonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideCategories: Arteriolar Smooth Muscle, Agents Acting On, Cytochrome P-450 SubstratesRasagiline
go.drugbank.com/drugs/DB01367ApprovedInvestigationalRasagiline is an irreversible inhibitor of monoamine oxidase and is used as a monotherapy in early Parkinson's disease or as an adjunct therapy in more advanced cases.
Synonyms: (R)-N-2-Propynyl-1-indanamine, (1R)-N-propargylindan-1-amineCategories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 SubstratesLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalLarotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays … an important role in tumor cell growth and survival.
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: VITRAKVI®CÁPSULAS DE 100MG, VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 MLMethylene blue
go.drugbank.com/drugs/DB09241ApprovedInvestigationalIts use as an urinary tract antiseptic has also been investigated. … clinical trials to be an inhibitor of Tau protein aggregation.
Mixtures: UR N-C Urinary Antiseptic, Me NaPhos MB Hyo 1Categories: Monoamine Oxidase A Inhibitors for interaction with Monoamine Oxidase A substrates, MATE 1 Inhibitors