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EPC2407
go.drugbank.com/drugs/DB05189InvestigationalIt is intended for the treatment of advanced cancer patients with solid tumors that are well vascularized.
Polyvalent antigen-KLH conjugate vaccine
go.drugbank.com/drugs/DB17565InvestigationalIt is under investigation in clinical trial NCT01223235 (Polyvalent Vaccine-klh Conjugate + Opt-821 Given in Combination With Bevacizumab).
AC-003
go.drugbank.com/drugs/DB22691Investigational[L53458] It is being investigated for the treatment of acute graft-versus-host disease (GVHD) and idiopathic pulmonary fibrosis (IPF).[L53458]
AVAC
go.drugbank.com/drugs/DB05441ExperimentalIt has been tested in uses related to asthma and in treating eczema and atopic dermatitis. … [Mycobacterium vaccae] is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of regulatory T-cells that surpress inappropriate
Glypromate
go.drugbank.com/drugs/DB05633ExperimentalIn December 2008, the company discontinued further development of the drug after it failed to show an observable effect.
ICA-105665
go.drugbank.com/drugs/DB06089InvestigationalIt is a novel opener of the KCNQ ion channel which in preclinical studies has demonstrated a broad spectrum of activity in models of epilepsy.
RO7284755
go.drugbank.com/drugs/DB17527InvestigationalRO7284755 is an investigational cancer drug: it is a PD-1-targeted IL-2 variant antibody fusion protein.
Sonpiretigene isteparvovec
go.drugbank.com/drugs/DB17844InvestigationalDeveloped by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP).
scAAV9.U7.ACCA
go.drugbank.com/drugs/DB18582InvestigationalDeveloped by Nationwide Children’s Hospital, it is being investigated for the treatment of Duchenne muscular dystrophy.
Recombinant Bacterial ACE2 Receptors-like Enzyme
go.drugbank.com/drugs/DB15741InvestigationalIt is being investigated for treating hypertension, myocardial fibrosis, and cardiac dysfunction.