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Anthrax immune globulin human
go.drugbank.com/drugs/DB09057ApprovedInvestigationalAnthrax immune globulin is a human antibody given with antibiotics for the treatment of anthrax. … It is derived from the plasma of humans immunized with BioThrax (adsorbed anthrax vaccine), which is then further purified.
Olaparib
go.drugbank.com/drugs/DB09074ApprovedInvestigationalOlaparib is a selective and potent inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, PARP1 and PARP2. … [A246015] Olaparib is used to treat a number of BRCA-associated tumours, including ovarian cancer, breast cancer, pancreatic cancer, and prostate cancer.
Synonyms: 4-(3-{[4-(cyclopropylcarbonyl)piperazin-1-yl]carbonyl}-4-fluorobenzyl)phthalazin-1(2H)-oneCategories: MATE 2-K Inhibitors, P-glycoprotein substrates with a Narrow Therapeutic IndexEdoxaban
go.drugbank.com/drugs/DB09075ApprovedInvestigationalEdoxaban is a member of the Novel Oral Anti-Coagulants (NOACs) class of drugs, and is a rapidly acting, oral, selective factor Xa inhibitor. … It is indicated to reduce the risk of stroke and systemic embolism (SE) in patients with nonvalvular atrial fibrillation (NVAF) and for the treatment of deep vein thrombosis (DVT) and pulmonary embolism
Categories: P-glycoprotein substrates, Heterocyclic Compounds, 1-RingNintedanib
go.drugbank.com/drugs/DB09079ApprovedInvestigationalbeing [Pirfenidone]) and as such is used as a first-line treatment following diagnosis to slow down the progressive loss of lung function. … [A185237] As a chemotherapeutic agent for NSCLC, nintedanib, in combination with [Docetaxel], is reserved for patients who have tried and failed first-line chemotherapeutic options.[L8459]
Synonyms: methyl (3Z)-3-[(4-{methyl[(4-methylpiperazin-1-yl)acetyl]amino}anilino)(phenyl)methylidene]-2-oxo-2,3-dihydro-1H-indole-6-carboxylateCategories: P-glycoprotein inhibitors, Cytochrome P-450 SubstratesOlodaterol
go.drugbank.com/drugs/DB09080ApprovedInvestigationalA once-a-day treatment with a LABA has several advantages over short-acting bronchodilators and twice-daily LABAs including improved convenience and compliance and improved airflow over a 24-hour period … It is by this mechanism that olodaterol is used for the treatment of chronic obstructive pulmonary disease (COPD) and the progressive airflow obstruction that is characteristic of it.
Mixtures: SPIOLTO®RESPIMAT®, SPIOLTO®RESPIMAT®Categories: Cytochrome P-450 Substrates, Adrenergic beta-1 Receptor AgonistsIvabradine
go.drugbank.com/drugs/DB09083ApprovedInvestigationalTherefore, as ivabradine is designed as a "pure" heart rate-lowering drug by selectively acting on the If channels, it may offer a more favorable side effect profile due to its lower likelihood of causing … Ivabradine is a novel heart rate lowering medicine for the symptomatic management of stable angina pectoralis and symptomatic chronic heart failure.
Synonyms: 3-[3-({[(7S)-3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-trien-7-yl]methyl}(methyl)amino)propyl]-7,8-dimethoxy-2,3,4,5-tetrahydro-1H-3-benzazepin-2-oneMixtures: CARIVALAN 25/5, CARIVALAN 6.25/5Benzydamine
go.drugbank.com/drugs/DB09084ApprovedInvestigationalBenzydamine (also known as Tantum Verde or Difflam), available as the hydrochloride salt, is a locally-acting nonsteroidal anti-inflammatory drug (NSAID) with local anaesthetic and analgesic properties … Moreover, unlike aspirin-like NSAIDs which are acids or metabolised to acids, benzydamine is in fact a weak base.
Mixtures: KLOROBEN FORT 3 MG/ML+ 2 MG/ML GARGARA, 200 ML, KLOROBEN FORT 3 MG/ML+ 2 MG/ML ORAL SPREY, 40 MLCategories: Non COX-2 selective NSAIDS, Heterocyclic Compounds, 1-RingTixocortol
go.drugbank.com/drugs/DB09091ApprovedWithdrawnTixocortol is a 21-thiol derivative of hydrocortisone classified as a class A corticosteroid. … It is a synthetic steroid with topical anti-inflammatory properties without the systemic glucocorticoid and mineralocorticoid activities and toxicity.[L1078]
Quinagolide
go.drugbank.com/drugs/DB09097ApprovedWithdrawnIt is typically present in the hydrochloride salt form and is marketed as oral tablets under the brand name Norprolac contained as a racemate. … Hyperprolalctinaemia is associated with gonadal dysfunction, including infertility and reduced libido, as well as long-term complications such as osteoporosis [A19684].
Synonyms: (+-)-N,N-Diethyl-N'-((3R*,4aR*,10aS*)-1,2,3,4,4a,5,10,10a-octahydro-6-hydroxy-1-propylbenzo(g)quinolin-3-yl)sulfamideCategories: Heterocyclic Compounds, 2-RingCoenzyme M
go.drugbank.com/drugs/DB09110ApprovedInvestigationalCoenzyme M (commonly known by its salt form, Mesna) is a synthetic sulfhydryl (thiol) compound and is used for prophylaxis of Ifosfamide and cyclophosphamide induced hemorrhagic cystitis.[A18572]
Synonyms: HS-CoM, Coenzym MCategories: Compounds used in a research, industrial, or household setting