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Displaying results 4871 - 4880 of 9134 in total
  1. Drug

    TM5614

    go.drugbank.com/drugs/DB16516
    Investigational

    An animal study in mice fed a fast-food diet with TM5614 treatment showed improved metabolic measurements and reduced liver steatosis[L31673,L31678]. … TM5614 is a novel, orally active, plasminogen activator inhibitor 1 (PAI-1) inhibitor[A228788,A228793,].

  2. Drug

    2-Methoxy-6-{(E)-[(4-methylphenyl)imino]methyl}phenol

    go.drugbank.com/drugs/DB13869
    Experimental

    TIMBD is an azaresveratrol analog.

  3. Drug

    Pegargiminase

    go.drugbank.com/drugs/DB06592
    Investigational

    Pegargiminase is an anticancer agent.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Ispectamab debotansine

    go.drugbank.com/drugs/DB18456
    Investigational

    Ispectamab debotansine is an antibody drug conjugate comprised of an anti-B cell maturation (BCMA) IgG1 humanized antibody conjugated covalently to the dibenzocyclooctyne (DBCO) noncleavable linker maytansinoid

  5. Drug

    LMB-100

    go.drugbank.com/drugs/DB18591
    Investigational

    LMB-100 is a is an antibody-toxin conjugate with an antimesothelin Fab linked to a 24-kilodalton portion of Pseudomonas exotoxin A with mutations that decrease immunogenicity.

  6. Drug

    Omburtamab

    go.drugbank.com/drugs/DB15635
    Investigational

    CD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.

  7. Drug

    Pyrethrum extract

    go.drugbank.com/drugs/DB11087
    Approved

    Pyrethrum-containing mixtures are used as a common insecticide to control specific pest species. Pyrethrum extract is also used used to treat head, body, and pubic lice infections. … Pyrethrin refers to a more refined extract of pyrethrum. While pyrethrum extract is composed of 6 esters, both organic compounds mediate insecticidal activities.

    Mixtures: Mata Piojos A Pediculicide Low FoamingCategories: Compounds used in a research, industrial, or household setting
  8. Drug

    XMT-1001

    go.drugbank.com/drugs/DB06069
    Investigational

    XMT-1001 is a polymer-based prodrug of camptothecin (CPT), a well-characterized topoisomerase I inhibitor with potent anti-tumor activity. … XMT-1001 has demonstrated an improved therapeutic window as compared with CPT and irinotecan in human tumor xenografts models

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Bafilomycin A1

    go.drugbank.com/drugs/DB06733
    Experimental

    The most commonly utilized bafilomycin is bafilomycin A1. This is a useful tool as it can prevent the re-acidification of synaptic vesicles once they have undergone exocytosis. … The bafilomycins refer to a category of toxic macrolide antibiotics that are derivatives of Streptomyces griseus.

    Synonyms: Bafilomycin A1
  10. Drug

    Carbopol 974P

    go.drugbank.com/drugs/DB05384
    ApprovedWithdrawn

    Carbopol 974P is a highly carboxylated polymer composed of lightly cross-linked polyacrylic acid with a broad-spectrum mechanism based on acidification of pathogens. … It is a gel that may help both block the spread of sexually transmitted diseases and reduce unwanted pregnancies.

    Categories: Compounds used in a research, industrial, or household setting