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Displaying results 4881 - 4890 of 7059 in total
  1. Drug

    Adefovir dipivoxil

    go.drugbank.com/drugs/DB00718
    Approved

    Adefovir dipivoxil, previously called bis-POM PMEA, with trade names Preveon and Hepsera, is an orally-administered acyclic nucleotide analog reverse transcriptase inhibitor (ntRTI) used for treatment of hepatitis B. It is ineffective ag...

    Synonyms: Adefovir di(pivaloyloxymethyl) esterInternational brands: A Di Xian, Dai Ding
  2. Drug

    Eletriptan

    go.drugbank.com/drugs/DB00216
    ApprovedInvestigational

    Eletriptan is a second generation triptan drug developed by Pfizer Inc for the treatment of migraine headaches.

    Products: ELETRIPTAN DOC GENERICI
  3. Drug

    Darexaban

    go.drugbank.com/drugs/DB12289
    Investigational

    Darexaban has been used in trials studying the prevention and basic science of Japanese, Caucasian, Thromboembolism, Pharmacodynamics, and Pharmacokinetics, among others.

    Categories: Factor Xa Inhibitors
  4. Drug

    Ramucirumab

    go.drugbank.com/drugs/DB05578
    ApprovedInvestigational

    By binding to VEGFR2, ramucirumab prevents binding of its ligands (VEGF-A, VEGF-C, and VEGF-D), thereby preventing VEGF-stimulated receptor phosphorylation and downstream ligand-induced proliferation, … Ramucirumab is a human monoclonal antibody (IgG1) against vascular endothelial growth factor receptor 2 (VEGFR2), a type II trans-membrane tyrosine kinase receptor expressed on endothelial cells.

  5. Drug

    Telbivudine

    go.drugbank.com/drugs/DB01265
    ApprovedWithdrawn

    Telbivudine is a synthetic thymidine nucleoside analog with specific activity against the hepatitis B virus.

    Synonyms: L-DT
  6. Drug

    Davunetide

    go.drugbank.com/drugs/DB12613
    Investigational

    Davunetide is derived from a naturally occurring neuroprotective brain protein known as activity dependent neuroprotective protein. … physical damage in the brain caused by neurofibrillary tangles, one of the two established pathological hallmarks that are common to amnestic mild cognitive impairment (aMCI) and Alzheimer's disease (AD

  7. Drug

    Betibeglogene autotemcel

    go.drugbank.com/drugs/DB16900
    ApprovedInvestigational

    [L42940] β-thalassemia is a condition caused by mutations in the β-globin gene (HBB) that leads to a significant decrease in the production of β-globin. … [L42940] BB305 LVV encodes β<sup>A-T87Q</sup>-globin, compensating for the lack of β-globin in these patients.

    Synonyms: Autologous CD34+ cells encoding βA-T87Q-Globin gene
  8. Drug

    Fludrocortisone

    go.drugbank.com/drugs/DB00687
    ApprovedInvestigational

    Fludrocortisone is a synthetic mineralocorticoid used in conjunction with [hydrocortisone] to replace missing endogenous corticosteroids in patients with adrenal insufficiency. … [A187169,A187187] It is functionally similar to [aldosterone], the body's primary endogenous mineralocorticoid, and is structurally analogous to [cortisol], differing only by a fluorine atom at the 9-position

  9. Drug

    Uracil mustard

    go.drugbank.com/drugs/DB00791
    Approved

    It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

    Synonyms: 5-(di-2-chloroethyl)aminouracil, 5-[di(β-chloroethyl)amino]uracil
  10. Drug

    Cinoxacin

    go.drugbank.com/drugs/DB00827
    ApprovedWithdrawn

    Synthetic antimicrobial related to oxolinic acid and nalidixic acid and used in urinary tract infections.