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Displaying results 4881 - 4890 of 9128 in total
  1. Drug

    (4R)-limonene

    go.drugbank.com/drugs/DB08921
    Investigational

    As the main odor constituent of citrus (plant family Rutaceae), D-limonene is used in food manufacturing and some medicines, e.g. as a flavoring to mask the bitter taste of alkaloids, and as a fragrant

  2. Drug

    Uridine diphosphate glucose

    go.drugbank.com/drugs/DB01861
    Experimental

    Also serves as a precursor of sucrose lipopolysaccharides, and glycosphingolipids. … Serves as a precursor of glycogen, can be metabolized into UDPgalactose and UDPglucuronic acid which can then be incorporated into polysaccharides as galactose and glucuronic acid.

  3. Drug

    Royal jelly

    go.drugbank.com/drugs/DB14250
    Investigational

    Royal jelly is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.

  4. Drug

    TSHA-105

    go.drugbank.com/drugs/DB18328
    Investigational

    TSHA-105 is an adeno-associated virus serotype 9 (AAV9) vector with an engineered transgene encoding the human SLC13A5 protein.

  5. Drug

    Axitinib

    go.drugbank.com/drugs/DB06626
    ApprovedInvestigational

    [L6676] Axitinib is an indazole derivative.[A179398] It is most commonly marketed under the name Inlyta® and is available in oral formulations. … Axitinib is a second generation tyrosine kinase inhibitor that works by selectively inhibiting vascular endothelial growth factor receptors (VEGFR-1, VEGFR-2, VEGFR-3).

    Categories: UGT1A1 Substrates with a Narrow Therapeutic Index, P-glycoprotein substrates with a Narrow Therapeutic IndexSynonyms: AR-14034
  6. Drug

    Linaclotide

    go.drugbank.com/drugs/DB08890
    ApprovedInvestigational

    [A260276] It is also a homolog of a heat-stable enterotoxin derived from _Escherichia coli_, the first natural ligand that activates GC-C. … Linaclotide is a synthetic 14-amino acid cyclic peptide [A260271] and first-in-class guanylate cyclase-C (G-CC) agonist.

  7. Drug

    Barnidipine

    go.drugbank.com/drugs/DB09227
    Investigational

    after a 1-year and 2-year follow-up period in 91% of the patients who had an initial response to the drug [A7842]. … Compared to several other calcium antagonists which are racemates, the barnidipine compound consisting of a single enantiomer may offer a high degree of pharmacological selectivity [A31567].

  8. Drug

    Regramostim

    go.drugbank.com/drugs/DB05386
    Investigational

    Regramostim (GM-CSF) is a differentially glycosylated factor produced mainly by activated T cells and macrophages. … Endothelial cells and fibroblasts can also produce GM-CSF after exposure to TNF-α, IL-1, IL-2 and IFN-γ. GM-CSF is found associated with extracellular matrix and in membrane-bound formats too.

    Synonyms: GM-CSF (CHO cell)
  9. Drug

    Palmidrol

    go.drugbank.com/drugs/DB14043
    InvestigationalNutraceutical

    Palmidrol is available for human use as a supplement (400 mg capsules) and as food for medical purposes In Italy and Spain (300 mg and 600 mg tablets). … A cannabinoid receptor-inactive eCB-related molecule used as prophylactic in helping to prevent respiratory viral infection.

  10. Drug

    Garden snail mucin

    go.drugbank.com/drugs/DB14244
    Investigational

    Garden snail mucin is an animal extract used in some OTC (over-the-counter) products. It is not an approved drug.