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Displaying results 481 - 490 of 1546 in total
  1. Drug

    Cilostazol

    go.drugbank.com/drugs/DB01166
    ApprovedInvestigational

    Cilostazol is a quinolinone derivative and antiplatelet agent with vasodilating properties that has been used in the symptomatic treatment of intermittent claudication in patients with peripheral ischaemia. It is marketed under the brand...

    Synonyms: 6-[4-(1-Cyclohexyl-1H-tetrazol-5-yl)-butoxy]-3,4-dihydro-1H-quinolin-2-one
  2. Drug

    Tivanisiran

    go.drugbank.com/drugs/DB19105
    Investigational

    Tivanisiran is under investigation in clinical trial NCT03108664 (HELIX, a Double-masked Study of SYL1001 in Patients With Moderate to Severe Dry Eye Disease (DED)).

    Synonyms: Rna, (a-a-g-c-g-c-a-u-c-u-u-c-u-a-c-u-u-c-a), complex with rna (u-g-a-a-g-u-a-g-a-a-g-a-u-g-c-g-c-u-u) (1:1)
  3. Drug

    Tirabrutinib

    go.drugbank.com/drugs/DB15227
    Investigational

    Tirabrutinib is under investigation in clinical trial NCT02626026 (Safety and Pharmacokinetics of GS-4059 in Healthy Volunteers and Subjects With Rheumatoid Arthritis (RA)).

    Synonyms: 6-amino-9-[(3R)-1-but-2-ynoylpyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one
  4. Drug

    Ebvaciclib

    go.drugbank.com/drugs/DB18967
    Investigational

    Ebvaciclib is under investigation in clinical trial NCT03519178 (A Study of PF-06873600 in People With Cancer).

    Synonyms: 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1- (methylsulfonyl)piperidin-4-yl) amino)pyrido(2,3-d)pyrimidin-7(8h)-one, Pyrido(2,3-d)pyrimidin-7(8h)-one, 6-(difluoromethyl)-8-((1r,2r)-2-hydroxy-2-methylcyclopentyl)-2-((1-(methylsulfonyl)-4-piperidinyl)amino)-
  5. Drug

    Deudomperidone

    go.drugbank.com/drugs/DB19055
    Investigational

    Deudomperidone is under investigation in clinical trial NCT05832151 (A Study to Evaluate the Efficacy and Safety of CIN-102 (Deudomperidone) in Adults With Diabetic Gastroparesis).

    Synonyms: 3-(3-(4-(5-chloro-2-oxo-3hbenzimidazol-1-yl)-1- piperidyl)propyl)-4,5,6,7- tetradeutero-1h-benzimidazol-2- one, 2h-benzimidazol-2-one-4,5,6,7-d4, 1-(3-(4-(5-chloro-2,3-dihydro-2-oxo-1h-benzimidazol-1-yl)-1-piperidinyl)propyl)-1,3-dihydro-
  6. Drug

    3-(4-Amino-2-Tert-Butyl-5-Methyl-Phenylsulfanyl)-6-Cyclopentyl-4-Hydroxy-6-[2-(4-Hydroxy-Phenyl)-Ethyl]-5,6-Dihydro-Pyran-2-One

    go.drugbank.com/drugs/DB04298
    Experimental

    Synonyms: 3-(4-Amino-2-Tert-Butyl-5-Methyl-Phenylsulfanyl)-6-Cyclopentyl-4-Hydroxy-6-[2-(4-Hydroxy-Phenyl)-Ethyl]-5,6-Dihydro-Pyran-2-One
  7. Drug

    Morin

    go.drugbank.com/drugs/DB16770
    Experimental

    Synonyms: 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-one
  8. Drug

    Luvadaxistat

    go.drugbank.com/drugs/DB16067
    Investigational

    Luvadaxistat is under investigation in clinical trial NCT03214588 (Efficacy, Tolerability, and Pharmacokinetics of Multiple Doses of Oral TAK-831 in Adults With Friedreich Ataxia).

    Synonyms: 4-HYDROXY-6-(2-(4-(TRIFLUOROMETHYL)PHENYL)ETHYL)-2,3-DIHYDROPYRIDAZIN-3-ONE
  9. Drug

    Linafexor

    go.drugbank.com/drugs/DB18031
    Investigational

    Synonyms: 1,2,4-OXADIAZOL-5(2H)-ONE, 3-(4-(3-((5-CYCLOPROPYL-3-(2,6-DICHLOROPHENYL)-4-ISOXAZOLYL)METHOXY)-8-AZABICYCLO(3.2.1)OCT-8-YL)-2-FLUOROPHENYL)-, 3-(4-((3-endo)-3-((5-cyclopropyl-3-(2,6-dichlorophenyl)isoxazol-4- yl)methoxy)-8-azabicyclo[3.2.1]octan-8-yl)-2-fluorophenyl)-1,2,4-oxadiazol-5(4H)-one
  10. Drug

    1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE]AMINO}UNDECAN-2-ONE

    go.drugbank.com/drugs/DB08364
    Experimental

    Synonyms: 1-{[(1E)-(3-HYDROXY-2-METHYL-5-{[(TRIHYDROXY-LAMBDA^5^-PHOSPHANYL)OXY]METHYL}PYRIDIN-4-YL)METHYLIDENE]AMINO}UNDECAN-2-ONE