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Displaying results 4891 - 4900 of 10000 in total
  1. Drug

    Elivaldogene autotemcel

    go.drugbank.com/drugs/DB16746
    Approved

    Elivaldogene autotemcel is a gene therapy consisting of genetically modified autologous cells. … [A243691] ALDP is a key protein that normally breaks down fatty substances in the body called very long-chain fatty acids (VLCFAs).

    International brands: Lenti-D
  2. Drug

    Plant-based virus-like particles, recombinant, adjuvanted COVID-19 vaccine

    go.drugbank.com/drugs/DB16757
    Approved

    [L40694] It is composed of VLPs expressing SARS-CoV-2 spike protein trimers (stabilized in a pre-fusion conformation) and is mixed with the AS03 adjuvant system prior to administration. … [A245819] Plant-based VLPs offer a number of advantages as compared to other vaccine platforms, including speed and ease of manufacturing and increased immunogenicity.

    Synonyms: Recombinant SARS-CoV-2 spike (S)-protein virus-like particle
  3. Drug

    STF-31

    go.drugbank.com/drugs/DB16761
    Experimental

    Categories: Heterocyclic Compounds, 1-Ring
  4. Drug

    Tyrphostin B44

    go.drugbank.com/drugs/DB16762
    Experimental

    Synonyms: Tyrphostin B-44Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Morin

    go.drugbank.com/drugs/DB16770
    Experimental

    Synonyms: 2-(2,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4h-1-benzopyran-4-one, Natural yellow 8Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  6. Drug

    Rhamnetin

    go.drugbank.com/drugs/DB16772
    Experimental

    Synonyms: 7-O-Methylquercetin, 7-MethoxyquercetinCategories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-Ring
  7. Drug

    Resamirigene bilparvovec

    go.drugbank.com/drugs/DB16779
    Investigational

    AT132 is under investigation in clinical trial NCT03199469 (Gene Transfer Clinical Study in X-linked Myotubular Myopathy).

    Synonyms: DNA (synthetic adeno-associated virus 8 vector AT132 human myotubularin cDNA-specifying), Non-replicating adeno-associated viral vector, serotype 8, expressing human myotubularin gene
  8. Drug

    Tefidsogene civaparvovec

    go.drugbank.com/drugs/DB16789
    Investigational

    It consists of an adeno-associated virus (AAV) type 2/6 vector and a zinc finger nuclease (ZFN) system that inserts a correct copy of the Iduronate 2-Sulfatase (IDS) gene into the albumin locus in hepatocytes

    Synonyms: EXONS 2-9 FROM HIDS AND A SPLICE ACCEPTOR SITE (SA), A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/6 (RAAV REP2-CAP6) VECTOR, WHICH CONTAINS A PROMOTER-LESS HUMAN IDURONATE 2-SULFATASE (HIDS) TRANSGENE CASSETTE, ENCODING PARTS OF EXON 1 PLUS
  9. Drug

    Devafidugene civaparvovec

    go.drugbank.com/drugs/DB16790
    Investigational

    It uses proprietary zinc finger nucleases (ZFN) that insert a functional copy of the alpha-L-iduronidase (IDUA) enzyme. … Developed by Sangamo Therapeutics, Inc., devafidugene civaparvovec is being investigated for the treatment of mucopolysaccharidosis Type I (MPS I).[L46716]

  10. Drug

    Delandistrogene moxeparvovec

    go.drugbank.com/drugs/DB16802
    ApprovedInvestigational

    [L47026] DMD is an X-linked genetic disorder characterized by mutations in the dystrophin gene, leading to a deficiency in functional dystrophin protein. … Microdystrophin is a truncated, functional form of dystrophin.