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Pivhydrazine
go.drugbank.com/drugs/DB09252ApprovedWithdrawnIn 1960, it was widely used as an antidepressant agent but it is now discontinued.
Linsitinib
go.drugbank.com/drugs/DB06075InvestigationalAn orally bioavailable small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF-1R) with potential antineoplastic activity. IGF-1R inhibitor OSI-906 selectively inhibits IGF-1R, which may result in the inhibition of tum...
Sodium sulfide
go.drugbank.com/drugs/DB11159ApprovedAlong with its hydrate form, sodium sulfide releases hydrogen sulfide (H2S) when in contact with moist air. … Interestingly, sodium sulfide was shown to have some cardioprotective role against cardiac ischemia or reperfusion injury, as well as protect lungs against ventilator-induced lung injury [A27275].
TAK-428
go.drugbank.com/drugs/DB05499ExperimentalTAK-428 is a drug for treating diabetic neuropathy. … It is based on the novel concept that peripheral nervous tissue that was damaged by diabetes can be repaired and regenerated by stimulating an increase in neurotrophic factors.
Brilaroxazine
go.drugbank.com/drugs/DB09226InvestigationalBrilaroxazine (RP5063) is an investigational atypical antipsychotic which is under development by Reviva Pharmaceuticals for the treatment of schizophrenia and schizoaffective disorder. … As of May 2015, it is in phase III clinical trials for schizophrenia.
Triazavirin
go.drugbank.com/drugs/DB15622Investigational[L12087] Given the similarities between SARS-CoV-2 and H5N1, health officials are investigating Triazavirin as an option to combat SARS-CoV-2, the coronavirus responsible for COVID-19.[A191625]
Categories: Antivirals for Systemic Use, Antiinfectives for Systemic UseAnti-SARS-CoV-2 IgY
go.drugbank.com/drugs/DB16356InvestigationalFrom there, the chicken antibodies are harvested from the egg yolks of the eggs laid by these chickens and formulated into the nasal drops that can be administered. … [L27381] To create these antibodies, chickens are injected in the chest with the spike protein, which is the surface protein of SARS-CoV-2; this results in an immune response mounted by the chickens towards
Valrubicin
go.drugbank.com/drugs/DB00385ApprovedUsed in the treatment of the bladder cancer, valrubicin is administered by direct infusion into the bladder.
Latrunculin B
go.drugbank.com/drugs/DB08080ExperimentalLatrunculin B is a 14-membered macrolide attached to 2-thiazolidinone moiety, isolated from Red Sea sponge _Latrunculia magnifica_.