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D-Tryptophan
go.drugbank.com/drugs/DB03225ExperimentalThe distinguishing structural characteristic of tryptophan is that it contains an indole functional group. It is an essential amino acid as defined by its growth effects on rats. … Tryptophan is one of the 20 standard amino acids, as well as an essential amino acid in the human diet. It is encoded in the standard genetic code as the codon UGG.
Oprozomib
go.drugbank.com/drugs/DB11991InvestigationalOprozomib has been used in trials studying the treatment of Solid Tumors, Multiple Myeloma, Waldenstrom Macroglobulinemia, Advanced Hepatocellular Carcinoma, and Advanced Non-Central Nervous System (CNS
BN‐Brachyury vaccine
go.drugbank.com/drugs/DB17425ExperimentalBN‐Brachyury vaccine is a novel prime‐boost therapeutic cancer immunotherapy. It is composed of the [MVA-BN-brachyury-TRICOM vaccine] and the fowlpox virus(FPV)‐Brachyury booster vaccine.[A255173]
Synonyms: BN‐Brachyury vaccine2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid
go.drugbank.com/drugs/DB19221Investigational2-(1-(1-(2-chlorophenyl)-2-methoxy-2-oxoethyl)-4-sulfanyl-3-piperidinylidene) acetic acid is under investigation in clinical trial NCT03774394 (Impact of Chronic Kidney Disease on Clopidogrel Effects in
Pimagedine
go.drugbank.com/drugs/DB05383InvestigationalIt is an advanced glycation end product inhibitor which manages diabetic nephropathy, either alone or in combination with other therapies. … It is beneficial in treating patients with diabetic nephropathy.
Pinatuzumab vedotin
go.drugbank.com/drugs/DB15432InvestigationalObinutuzumab in Participants With Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)). … Pinatuzumab vedotin is under investigation in clinical trial NCT01691898 (A Study of Pinatuzumab Vedotin (DCDT2980S) Combined With Rituximab or Polatuzumab Vedotin (DCDS4501A) Combined With Rituximab or
Probable ATP-dependent RNA helicase DDX6
go.drugbank.com/bio_entities/BE0002501TargetHumansEssential for the formation of P-bodies, cytosolic membrane-less ribonucleoprotein granules involved in RNA metabolism through the coordinated storage of mRNAs encoding regulatory functions (PubMed:25995375, PubMed:27342281, PubMed:31422...
Synonyms: DEAD box protein 6TZP-102
go.drugbank.com/drugs/DB16129InvestigationalTZP-102 is under investigation in clinical trial NCT01452815 (Affects of Once-daily Oral Administration of TZP-102 on the Treatment of Symptoms Associated With Diabetic Gastroparesis).
Amedalin
go.drugbank.com/drugs/DB09188ExperimentalIt has no significant effect on reuptake of serotonin and dopamine and no antihistamine or anticholinergic properties. This drug was never marketed. … Amedalin is a selective norepinephrine reuptake inhibitor developed in the 1970s.
Lesopitron
go.drugbank.com/drugs/DB04970ExperimentalLesopitron is an anxiolytic with pre- and post-synaptic 5-HT1A agonist activity, which is under development by Esteve.