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Displaying results 4971 - 4980 of 10000 in total
  1. Drug

    Ibrigampar

    go.drugbank.com/drugs/DB05490
    Investigational

    T131 is not structurally related to the thiazolidinedione class of PPARg agonists, which includes Actos and Avandia. … AMG-131 (T131), an orally-administered therapy, is expected to lower blood glucose in type II diabetic patients by improving the body’s ability to respond to insulin.

  2. Drug

    Alglucosidase alfa

    go.drugbank.com/drugs/DB01272
    ApprovedInvestigational

    It is encoded by the most predominant of nine observed haplotypes of this gene. Aglucosidase alfa is produced by recombinant DNA technology in a Chinese hamster ovary cell line. … It is used for the treatment of Pompe disease (GAA deficiency) in infants and pediatric patients.

  3. Drug

    Pentostatin

    go.drugbank.com/drugs/DB00552
    ApprovedInvestigational

    It is also synergistic with some other antineoplastic agents and has immunosuppressive activity. … The drug is effective in the treatment of many lymphoproliferative malignancies, particularly hairy-cell leukemia.

  4. Drug

    DG051

    go.drugbank.com/drugs/DB05177
    Experimental

    DG051 is a novel small-molecule inhibitor of leukotriene A4 hydrolase (LTA4H), the protein made by one of the genes in the leukotriene pathway that has been shown to link to risk of heart attack. … DG051 is designed to decrease risk of heart attack by decreasing the production of leukotriene B4 (LTB4), an end product of the leukotriene pathway and a potent promoter of inflammation.

  5. Drug

    Talastine

    go.drugbank.com/drugs/DB13349
    Experimental

    Categories: Antihistamines for Systemic Use
  6. Drug

    ILY101

    go.drugbank.com/drugs/DB05059
    Investigational

    ILY101 is a metal-free, non-absorbed polymeric drug designed for the selective binding and removal of phosphate anions from the gastrointestinal tract. … ILY101 is designed to allow for lower daily doses and improved patient acceptance and tolerability in comparison to other products in this class of drugs.

  7. Drug

    Dapoxetine

    go.drugbank.com/drugs/DB04884
    Investigational

    Dapoxetine is a selective serotonin reuptake inhibitor, for the treatment of premature ejaculation. … In a phase II proof-of-concept study conducted by PPD, dapoxetine demonstrated a statistically significant increase in ejaculatory latency when compared to placebo.

    Categories: Genito Urinary System and Sex Hormones
  8. Drug

    PR-104

    go.drugbank.com/drugs/DB05968
    Investigational

  9. Drug

    ATHX-105

    go.drugbank.com/drugs/DB06008
    Investigational

    ATHX-105 is an investigational selective 5HT2c receptor agonist developed by Athersys Inc. for the treatment of Obesity.

  10. Drug

    Pascolizumab

    go.drugbank.com/drugs/DB06560
    Investigational

    Pascolizumab (SB 240683) is a humanized anti-interleukin-4 antibody with therapeutic potential in asthma.