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Displaying results 4971 - 4980 of 8171 in total
  1. Drug

    Beeswax

    go.drugbank.com/drugs/DB11600
    Approved

    The wax obtained from the honeycomb of the bee. It consists primarily of myricyl palmitate, cerotic acid esters and some high-carbon paraffins. Beeswax is used as a stiffening agent in ointments and creams, and enables water to be incorp...

  2. Drug

    PMI-001

    go.drugbank.com/drugs/DB05730
    Experimental

    It is an extract of the roots of an undisclosed perennial shrub which interferes with the production of IL-2 and COX-2 proteins, for the potential treatment of autoimmune diseases, such as rheumatoid arthritis

  3. Drug

    MEM 1414

    go.drugbank.com/drugs/DB05888
    Experimental

    MEM 1414 works by blocking phosphodiesterase, an enzyme that breaks down an important brain chemical, cyclic AMP. It appears to work in the area of the brain where new memories are formed.

  4. Drug

    (1S,2R,3S,4R,5R)-2,3,4-trihydroxy-N-octyl-6-oxa-8-azabicyclo[3.2.1]octane-8-carbothioamide

    go.drugbank.com/drugs/DB08260
    Experimental

    These are compounds containing an oxepane ring, which is an a seven-member saturated aliphatic heterocycle with one oxygen and six carbon atoms. This drug targets the protein beta-glucosidase A.

  5. Drug

    XL784

    go.drugbank.com/drugs/DB04991
    Investigational

    XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. XL784 was specifically optimized to be MMP-1 sparing, thu...

  6. Drug

    Chymotrypsin

    go.drugbank.com/drugs/DB09375
    ApprovedInvestigationalVet approvedWithdrawn

    Chymotrypsin (EC 3.4.21.1) is a digestive enzyme that promotes proteolysis, or the breakdown of proteins and polypeptides. It is a serine protease synthesized in the pancreas and is a vital component in the pancreatic juice. Like most pr...

  7. Drug

    Velagliflozin

    go.drugbank.com/drugs/DB20686
    Experimental

    Velagliflozin has a monoisotopic molecular weight of 395.17 Da.

  8. Drug

    Intiquinatine

    go.drugbank.com/drugs/DB20708
    Experimental

    Intiquinatine has a monoisotopic molecular weight of 387.01 Da.

  9. Drug

    Isbogrel

    go.drugbank.com/drugs/DB20766
    Experimental

    Isbogrel has a monoisotopic molecular weight of 281.14 Da.

  10. Drug

    Besigomsin

    go.drugbank.com/drugs/DB20894
    Experimental

    Besigomsin has a monoisotopic molecular weight of 416.18 Da.

    Categories: P-glycoprotein inhibitors, Cytochrome P-450 Substrates