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Psilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.
Squaric acid dibutyl ester
go.drugbank.com/drugs/DB12223InvestigationalSquaric acid dibutyl ester is under investigation in clinical trial NCT01971385 (Safety and Efficacy of Squaric Acid Dibutyl Ester for the Treatment of Herpes Labialis).
Milvexian
go.drugbank.com/drugs/DB16233InvestigationalMilvexian is under investigation in clinical trial NCT03766581 (A Study on BMS-986177 for the Prevention of a Stroke in Patients Receiving Aspirin and Clopidogrel).
Tilsotolimod
go.drugbank.com/drugs/DB16341InvestigationalTilsotolimod is under investigation in clinical trial NCT03865082 (Study of Tilsotolimod in Combination With Nivolumab and Ipilimumab for the Treatment of Solid Tumors (ILLUMINATE-206)).
WP-1122
go.drugbank.com/drugs/DB17192InvestigationalIt was granted FDA orphan designation for the treatment of glioblastoma multiforme.[L47361]
ATX-F8-117
go.drugbank.com/drugs/DB17712ExperimentalDeveloped by Apitope, it is being investigated for the treatment of hemophilia A.[L46163]
mRNA-3351
go.drugbank.com/drugs/DB17718ExperimentalDeveloped by Moderna, it is currently being investigated as the treatment for Crigler-Najjar syndrome
inBreath airway transplant system
go.drugbank.com/drugs/DB18692ExperimentalinBreath airway transplant system composes of a scaffold seeded with autologous bone marrow cells and incubated in the bioreactor for two days prior to implant.
GLB-005
go.drugbank.com/drugs/DB32797ExperimentalGLB-005 is a molecular glue degrader targeting WIZ and is being investigated for treatment of sickle cell disease and β-thalassemia.[L56125, L56126, L56128]
Calcitonin gene-related peptide
go.drugbank.com/drugs/DB06379InvestigationalA 37-amino acid peptide derived from the calcitonin gene. It occurs as a result of alternative processing of mRNA from the calcitonin gene. The neuropeptide is widely distributed in the brain, gut, perivascular nerves, and other tissue. ...