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Hydrocortisone aceponate

Ditiocarb

A chelating agent that has been used to mobilize toxic metals from the tissues of man and experimental animals. It is the main metabolite of DISULFIRAM.

CZEN 002

The antimicrobial activity of CZEN-002 is unique in that it does not depend on direct damage to the microbial membrane. … It appears that CZEN-002 works on a receptor in yeast that has yet to be identified.

Talaporfin

Talaporfin has been investigated for the treatment of Port-Wine Stain and Benign Prostatic Hyperplasia.

Sodium lauryl sulfoacetate

Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.

Leukotriene D4

Leukotriene D4 has been used in trials studying the diagnostic of Asthma and Allergic Rhinitis.

Enlicitide

PCSK9 binds low-density lipoprotein receptors (LDLR) on the surface of hepatocytes and promotes their degradation within the liver; by blocking this interaction, enlicitide increases the number of LDLRs … Enlicitide is a macrocyclic peptide inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).

Fallypride

Fallypride is under investigation in clinical trial NCT02310360 (Striatal and Extra-striatal Dopamine Release in Response to Food in Healthy Humans).

TGAAC94

The Health Recombinant DNA Advisory Committee (RAC) concluded that a possible role of the gene transfer in this clinical course could not definitively be excluded due to the lack of data. [A264038] … It was under investigation in clinical trials to treat Inflammatory Arthritis. In 2007, one patient participating in the clinical trial died and the trial was placed on clinical hold by the FDA.

Pracinostat

Data demonstrate that Pracinostat is a potent and effective anti-tumor drug with potential as an oral therapy for a variety of human hematological and solid tumors. … Pracinostat is a novel HDAC inhibitor with improved in vivo properties compared to other HDAC inhibitors currently in clinical trials, allowing oral dosing.