Sodium lauryl sulfoacetate
Identification
- Name
- Sodium lauryl sulfoacetate
- Accession Number
- DB13157
- Description
Sodium lauryl sulfoacetate is a wetting agent and surfactant used in enema-type laxative products.
- Type
- Small Molecule
- Groups
- Approved, Experimental
- Structure
Structure for Sodium lauryl sulfoacetate (DB13157)
- Weight
- Average: 330.41
Monoisotopic: 330.14768942 - Chemical Formula
- C14H27NaO5S
- Synonyms
- Lathanol
- Lathanol LAL
- Sulfoacetic acid dodecyl ester S-sodium salt
Pharmacology
Accelerate your drug discovery research with the industry’s only fully connected ADMET dataset, ideal for:Accelerate your drug discovery research with our fully connected ADMET dataset- Indication
Sodium lauryl sulfoacetate is not an active pharmacological ingredient in pharmaceutical preparations and so has no official indication.
- Associated Conditions
- Associated Therapies
- Contraindications & Blackbox Warnings
Contraindications & Blackbox WarningsWith our commercial data, access important information on dangerous risks, contraindications, and adverse effects.Our Blackbox Warnings cover Risks, Contraindications, and Adverse Effects- Pharmacodynamics
Sodium lauryl sulfoacetate acts as a wetting agent and surfactant in pharmaceutical preparations 1. It is currently used in enema-type laxatives.
- Mechanism of action
- Not Available
- Absorption
- Not Available
- Volume of distribution
- Not Available
- Protein binding
- Not Available
- Metabolism
- Not Available
- Route of elimination
- Not Available
- Half-life
- Not Available
- Clearance
- Not Available
- Adverse Effects
Reduce medical errorsand improve treatment outcomes with our comprehensive & structured data on drug adverse effects.Reduce medical errors & improve treatment outcomes with our adverse effects data- Toxicity
- Not Available
- Affected organisms
- Not Available
- Pathways
- Not Available
- Pharmacogenomic Effects/ADRs
- Not Available
Interactions
- Drug Interactions
- This information should not be interpreted without the help of a healthcare provider. If you believe you are experiencing an interaction, contact a healthcare provider immediately. The absence of an interaction does not necessarily mean no interactions exist.Not Available
- Food Interactions
- No interactions found.
Products
Comprehensive & structured drug product infoFrom application numbers to product codes, connect different identifiers through our commercial datasets.Easily connect various identifiers back to our datasets- Mixture Products
Name Ingredients Dosage Route Labeller Marketing Start Marketing End Region Image Microlax Micro Enema Sodium lauryl sulfoacetate (9 mg) + Sodium citrate (90 mg) + Sorbitol (625 mg) Enema; Liquid Rectal Mcneil Consumer Healthcare Division Of Johnson & Johnson Inc 1995-12-31 2020-08-06 Canada 
Microlax Micro-enema Sodium lauryl sulfoacetate (9 g) + Sodium citrate (90 g) + Sorbitol (625 g) Liquid Rectal Kabi Pharmacia Canada Inc. 1993-12-31 1996-09-10 Canada
Categories
- ATC Codes
- A06AG11 — Sodium lauryl sulfoacetate, incl. combinations
- Drug Categories
- Chemical TaxonomyProvided by Classyfire
- Description
- This compound belongs to the class of organic compounds known as organosulfonic acids. These are compounds containing the sulfonic acid group, which has the general structure RS(=O)2OH (R is not a hydrogen atom).
- Kingdom
- Organic compounds
- Super Class
- Organic acids and derivatives
- Class
- Organic sulfonic acids and derivatives
- Sub Class
- Organosulfonic acids and derivatives
- Direct Parent
- Organosulfonic acids
- Alternative Parents
- Sulfonyls / Alkanesulfonic acids / Carboxylic acid esters / Monocarboxylic acids and derivatives / Organic sodium salts / Organic oxides / Hydrocarbon derivatives / Carbonyl compounds / Organic cations
- Substituents
- Aliphatic acyclic compound / Alkanesulfonic acid / Carbonyl group / Carboxylic acid derivative / Carboxylic acid ester / Hydrocarbon derivative / Monocarboxylic acid or derivatives / Organic alkali metal salt / Organic cation / Organic oxide
- Molecular Framework
- Aliphatic acyclic compounds
- External Descriptors
- Not Available
Chemical Identifiers
- UNII
- D0Y70F2B9J
- CAS number
- 1847-58-1
- InChI Key
- UAJTZZNRJCKXJN-UHFFFAOYSA-M
- InChI
- InChI=1S/C14H28O5S.Na/c1-2-3-4-5-6-7-8-9-10-11-12-19-14(15)13-20(16,17)18;/h2-13H2,1H3,(H,16,17,18);/q;+1/p-1
- IUPAC Name
- sodium 2-(dodecyloxy)-2-oxoethane-1-sulfonate
- SMILES
- [Na+].CCCCCCCCCCCCOC(=O)CS([O-])(=O)=O
References
- General References
- US Patent 3211614 [Link]
- External Links
- PubChem Compound
- 23668827
- PubChem Substance
- 347829267
- ChemSpider
- 15024
- 314832
- Wikipedia
- Sodium_citrate/sodium_lauryl_sulfoacetate/glycerol
Clinical Trials
Pharmacoeconomics
- Manufacturers
- Not Available
- Packagers
- Not Available
- Dosage Forms
Form Route Strength Enema Rectal 4.465 g/5ml Enema Rectal 45 mg Enema; liquid Rectal Liquid Rectal Emulsion Rectal 900 mg - Prices
- Not Available
- Patents
- Not Available
Properties
- State
- Solid
- Experimental Properties
- Not Available
- Predicted Properties
Property Value Source Water Solubility 0.00576 mg/mL ALOGPS logP 4.49 ALOGPS logP 4 ChemAxon logS -4.8 ALOGPS pKa (Strongest Acidic) -1.1 ChemAxon pKa (Strongest Basic) -7.3 ChemAxon Physiological Charge -1 ChemAxon Hydrogen Acceptor Count 4 ChemAxon Hydrogen Donor Count 0 ChemAxon Polar Surface Area 83.5 Å2 ChemAxon Rotatable Bond Count 14 ChemAxon Refractivity 77.32 m3·mol-1 ChemAxon Polarizability 34.95 Å3 ChemAxon Number of Rings 0 ChemAxon Bioavailability 1 ChemAxon Rule of Five Yes ChemAxon Ghose Filter Yes ChemAxon Veber's Rule No ChemAxon MDDR-like Rule No ChemAxon - Predicted ADMET Features
- Not Available
Spectra
- Mass Spec (NIST)
- Not Available
- Spectra
Spectrum Spectrum Type Splash Key Predicted GC-MS Spectrum - GC-MS Predicted GC-MS Not Available
Drug created on December 05, 2016 03:16 / Updated on June 12, 2020 16:53