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DTx-1252
go.drugbank.com/drugs/DB18086ExperimentalDTx-1252 is a siRNA therapeutic under investigation for the treatment of Charcot-Marie-Tooth Disease type 1A (CMTD1A).[L48096]
CSIC002
go.drugbank.com/drugs/DB18584ExperimentalCSIC002 is a small-molecule Sema-3A inhibitor. It is being investigated for the treatment of anterior ischemic optic neuropathy.
Benmelstobart
go.drugbank.com/drugs/DB17473InvestigationalAPL 502 is a humanised immunoglobulin G1 (IgG1) monoclonal antibody targeting the programmed cell death-1 ligand-1 (PD-L1).
Synonyms: 贝莫苏拜单抗, gamma1 heavy chain humanized (1-446) [VH (Homo sapiens IGHV2-5*01 (78.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.7.10] (26-33.51-57.96-105)) (1-116)-Homo sapiens IGHG1*01, G1m17,1 CH1 K120, CH3 D12, L14Lofexidine
go.drugbank.com/drugs/DB04948ApprovedInvestigationalLofexidine is a non-opioid centrally acting alpha2-adrenergic receptor agonist that was first approved for the treatment of opioid withdrawal in the United Kingdom in 1992. … [T210] Lofexidine was then repurposed for the treatment of opioid withdrawal, as it was seen to be more economical and have fewer side effects than clonidine.
Synonyms: 2-(alpha-(2,6-Dichlorophenoxy)ethyl)2-imidazolineCategories: MATE 1 Inhibitors, Cytochrome P-450 SubstratesBermekimab
go.drugbank.com/drugs/DB14947InvestigationalBermekimab is under investigation in clinical trial NCT01384630 (Safety, Pharmacokinetics, and Efficacy of RA-18C3 in Subjects With Moderate to Severe Psoriasis).
Synonyms: RA-18C3CH-1504 L-isomer
go.drugbank.com/drugs/DB19052InvestigationalCH-1504 L-isomer is under investigation in clinical trial NCT01116141 (A Study of CH-4051 in Patients With Rheumatoid Arthritis (RA)).
Synonyms: L-m-trex, L-mobiletrexPirinixic acid
go.drugbank.com/drugs/DB20300ExperimentalPirinixic acid is a small molecule drug. Pirinixic acid has a monoisotopic molecular weight of 323.05 Da.
Categories: Heterocyclic Compounds, 1-RingValproate pivoxil
go.drugbank.com/drugs/DB20420ExperimentalValproate pivoxil is a small molecule drug. Valproate pivoxil has a monoisotopic molecular weight of 258.18 Da.
Piridronic acid
go.drugbank.com/drugs/DB20475ExperimentalPiridronic acid is a small molecule drug. Piridronic acid has a monoisotopic molecular weight of 267.01 Da.
Cefcanel daloxate
go.drugbank.com/drugs/DB20582ExperimentalCefcanel daloxate is a small molecule drug. Cefcanel daloxate has a monoisotopic molecular weight of 661.1 Da.
Categories: Heterocyclic Compounds, 2-Ring