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Daclatasvir Action Pathway
smpdb.ca/view/SMP0125943Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … The nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the structural components of HCV virions.
Velpatasvir Action Pathway
smpdb.ca/view/SMP0125945Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … The nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the structural components of HCV virions.
Boceprevir Action Pathway
smpdb.ca/view/SMP0125956Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … , and NS5B.
Dasabuvir Action Pathway
smpdb.ca/view/SMP0125947Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … The nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the structural components of HCV virions.
Pibrentasvir Action Pathway
smpdb.ca/view/SMP0125949Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … The nucleocapsid protein core and the two envelope proteins E1 and E2 form the N terminus of the polyprotein and are the structural components of HCV virions.
Paritaprevir Action Pathway
smpdb.ca/view/SMP0125954Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … NS5A, and NS5B.
Telaprevir Action Pathway
smpdb.ca/view/SMP0125955Drug actionThe lipoviroparticles attach to LDL-R and SR-B1, and then the virus binds to CD81 and subsequently claudin-1 and occludin, which mediate the late steps of viral entry. … NS5A, and NS5B.
Cilgavimab Action Pathway
smpdb.ca/view/SMP0126002Drug actionThis prevents viral replication and propagation. … Cilgavimab inhibits S glycoprotein by blocking the interaction between it and the host ACE2 protein. This inhibits the binding and entry of the virion into the host cell.
Tixagevimab Action Pathway
smpdb.ca/view/SMP0126023Drug actionThis prevents viral replication and propagation. … Cilgavimab inhibits S glycoprotein by blocking the interaction between it and the host ACE2 protein. This inhibits the binding and entry of the virion into the host cell.
Sorafenib Action Pathway
smpdb.ca/view/SMP0122742Drug actionIt is an inhibitor of the RAF kinase protein and cell surface kinases PDGF-beta receptor, VEGF 2 and 3 receptor (many sources also say VEGFR 1), c-KIT receptor, and FLT-3 receptor. … C-KIT and FLT-3 on tumor cells are inhibited causing their proliferation to stop and the PDGF and VEGF receptors on endothelial cells are inhibited to stop the growth of new blood vessels that bring blood