Search
Pegcetacoplan
go.drugbank.com/drugs/DB16694ApprovedInvestigationalPegcetacoplan is a complement inhibitor indicated in the treatment of paroxysmal nocturnal hemoglobinuria (PNH). … [A235000,A235005] Pegcetacoplan was developed out of a need for an inhibitor of complement mediated hemolysis further upstream of C5.
Products: EMPAVELI® 54 MG/ML SOLUCIÓN INYECTABLEAnifrolumab
go.drugbank.com/drugs/DB11976ApprovedInvestigationalAnifrolumab, or MEDI-546, is a type 1 interferon receptor (IFNAR) inhibiting IgG1κ monoclonal antibody indicated in the treatment of adults with moderate to severe systemic lupus erythematosus. … [A237079,L34929] Three monoclonal antibodies (anifrolumab, [rontalizumab], and [sifalimumab]) that target the type 1 interferon pathway entered clinical trials as potential treatments for systemic lupus
Categories: Type I Interferon Receptor AntagonistProducts: Saphnelo 300 mg/2 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 ADETImidafenacin
go.drugbank.com/drugs/DB09262InvestigationalImidafenacin is an antispasmodic agent with anticholinergic effects. It antagonizes muscarinic receptors in the bladder to reduce the frequency of urination in the treatment of overactive bladder. It is marketed in Japan under the traden...
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesOmburtamab
go.drugbank.com/drugs/DB15635InvestigationalCD276 (B7-H3) is a B7/CD28 immunoglobulin superfamily member frequently expressed among solid human tumours.
Tick-borne encephalitis vaccine (whole virus, inactivated)
go.drugbank.com/drugs/DB16611ApprovedInvestigational[A237505] TBE often manifests in a biphasic manner, with patients experiencing a flu-like illness followed by a variable asymptomatic period and then a second phase characterized by various neurological … [A237520, L36050] Although TICOVAC was originally based on a master seed virus passaged in mouse brain and then propagated in chicken embryo fibroblast (CEF) cells, since the 1990's, the whole process
Niacin
go.drugbank.com/drugs/DB00627ApprovedInvestigationalNutraceuticalNiacin is a B vitamin used to treat vitamin deficiencies as well as hyperlipidemia, dyslipidemia, hypertriglyceridemia, and to reduce the risk of myocardial infarctions.
Mixtures: B-KOMP ENJEKSIYONLUK ÇÖZELTI IÇEREN AMPUL, 5 ADET, Formula F L WCategories: Vitamin B Complex, Cytochrome P-450 CYP2D6 InhibitorsFezolinetant
go.drugbank.com/drugs/DB15669ApprovedInvestigational[A259591,A259542] Lower estrogen levels during menopause will decrease the estrogen-mediated feedback loop and increase neurokinin B signalling, increasing the activity of KNDy neurons and therefore the … [A259591,A259596] Although mostly considered a nuisance, vasomotor symptoms can significantly affect quality of life, as women with 7 or more moderate to severe VMS daily have reported a decline in sleep
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP1A2 SubstratesOpium
go.drugbank.com/drugs/DB11130ApprovedIllicitThere is some legal production of opium in different countries for the obtention of alkaloids by extraction.[L1766] … It has been known for a long time, and the first evidence of a poppy culture dates from 5 thousand years by the Sumerians.
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP3A SubstratesEtizolam
go.drugbank.com/drugs/DB09166InvestigationalIt is not approved for use by FDA in the US; however it remains unscheduled in several states and is legal for research purposes. … Etizolam is a thienodiazepine which is chemically related to benzodiazepine (BDZ) drug class; it differs from BDZs in having a benzene ring replaced with a thiophene ring.
Categories: Cytochrome P-450 Substrates, Heterocyclic Compounds, 2-RingSynonyms: 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepineBenzalkonium
go.drugbank.com/drugs/DB11105ApprovedInvestigationalBenzalkonium is a quaternary ammonium compound used as a biocide, a cationic surfactant, and as a phase transfer agent [FDA Label]. … This salt is used in a great variety of international pharmaceutical products such as eye, ear, and nasal drops or sprays as an excipient ingredient serving as an antimicrobial preservative [FDA Label]
Mixtures: Hands First 4 in 1, Adventure Medical Kits 1-4 Person First AidCategories: Compounds used in a research, industrial, or household setting