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Displaying results 41 - 50 of 10000 in total
  1. Drug

    Nifedipine

    go.drugbank.com/drugs/DB01115
    ApprovedInvestigational

    Nifedipine, or BAY a 1040, is a first generation dihydropyridine L-type calcium channel blocker, similar to [nicardipine].

    Products: ANHITEN-A, NIFEDIPIN AL 5
  2. Drug

    Atenolol

    go.drugbank.com/drugs/DB00335
    ApprovedInvestigational

    Atenolol is a cardioselective beta-blocker used in a variety of cardiovascular conditions. … [A235850,A235855] A Cochrane review of patients being treated for primary hypertension shows that atenolol shows a risk ratio of 0.88 for cardiovascular disease risk and a risk ratio of 0.99 for mortality

    Mixtures: Aa-atenidone, Aa-atenidoneCategories: Adrenergic beta-1 Receptor Antagonists
  3. Drug

    Bisacodyl

    go.drugbank.com/drugs/DB09020
    ApprovedInvestigational

    Bisacodyl, a diphenylmethane derivative, is a commonly used over the counter stimulant laxative for occasional constipation. … [A233290,A233300,A207700] Bisacodyl was patented on 25 September 1956[L33045] but has been used as a laxative since 1952.[A233300]

    Products: K.B. BISCOD TABLET, Lax-A Go
  4. Drug

    Procaine

    go.drugbank.com/drugs/DB00721
    ApprovedInvestigationalVet approved

    A local anesthetic of the ester type that has a slow onset and a short duration of action. It is mainly used for infiltration anesthesia, peripheral nerve block, and spinal block. … Procaine has also been investigated as an oral entry inhibitor in treatment-experienced HIV patients [L1215].

    Categories: NMDA Receptor AntagonistsProducts: SATYA®AL 1%, PROCAINA AL 1%
  5. Drug

    Ursodeoxycholic acid

    go.drugbank.com/drugs/DB01586
    ApprovedInvestigational

    Ursodeoxycholic acid (UDCA), also known as ursodiol, is a naturally-occurring bile acid that constitutes a minor fraction of the human bile acid pool. … [A256272,A256277] UDCA has been used to treat liver disease for decades: its first use in traditional medicine dates back more than a hundred years.

    Products: PRESTALIX AU, Ag-ursodiol
  6. Drug

    Rizatriptan

    go.drugbank.com/drugs/DB00953
    ApprovedInvestigational

    Rizatriptan is a second-generation triptan [A258918] and a selective 5-HT<sub>1B and 5-HT1D</sub> receptor agonist.

    Categories: Monoamine Oxidase A Substrates, Serotonin Receptor AgonistsProducts: Ag-rizatriptan ODT, RIZATRIPTAN AL 5MG TABL
  7. Drug

    Zolpidem

    go.drugbank.com/drugs/DB00425
    ApprovedInvestigational

    Zolpidem, also known as _Ambien_, is a hypnotic drug that was initially approved by the FDA in 1992 [FDA label]. Zolpidem improves sleep in patients with insomnia. … Research also shows that zolpidem is rapid and effective in restoring brain function for patients in a vegetative state following brain injury.

    Categories: GABA-A Receptor Agonists, gamma-Aminobutyric Acid A Receptor Positive ModulatorSynonyms: N,N,6-Trimethyl-2-(4-methylphenyl)imidazo(1,2-a)pyridine-3-acetamide
  8. Drug

    SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)

    go.drugbank.com/drugs/DB18705
    Approved

    Bimervax is an adjuvanted non-mRNA COVID-19 vaccine utilizing a SARS-CoV-2 recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer. … [L48902,L48907] Bimervax was issued marketing authorization in the EU in March 2023 for use as a booster dose in patients who have previously received an mRNA COVID-19 vaccine.[L48907]

    Synonyms: SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer – B.1.351-B.1.1.7 strains, SARS-CoV-2 virus recombinant spike (S) protein receptor binding domain (RBD) fusion heterodimer (B.1.351-B.1.1.7 strains)
  9. Drug

    Losartan

    go.drugbank.com/drugs/DB00678
    ApprovedInvestigational

    Losartan is an angiotensin II receptor blocker (ARB) used to treat hypertension. … [L7423] Losartan is available as losartan potassium oral tablets as well as a combination tablet of losartan potassium and hydrochlorothiazide.

    Mixtures: Ag-losartan Hctz, Ag-losartan HctzCategories: Angiotensin 2 Receptor Blocker, Angiotensin II receptor antagonists
  10. Drug

    Toll-like receptor 9

    go.drugbank.com/drugs/DB15320
    Investigational

    Toll-like receptor 9 is under investigation in clinical trial NCT03007732 (Pembrolizumab in Combination With Intratumoral SD-101 Therapy).

    Categories: Toll-Like Receptor 9, agonistsSynonyms: Toll-like receptor 9