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Displaying results 41 - 50 of 353 in total
  1. Drug

    RTL-1000

    go.drugbank.com/drugs/DB17946
    Investigational

    RTL-1000 is a recombinant T-Cell receptor ligand being investigated for the treatment of multiple sclerosis.

    Synonyms: Recombinant t-cell receptor ligand rtl-1000, Rtl-1000 (recombinant t-cell receptor ligand)
  2. Drug

    Icanbelimod

    go.drugbank.com/drugs/DB21572
    Experimental

    Icanbelimod is a small molecule drug. The usage of the INN stem '-imod' in the name indicates that Icanbelimod is a immunomodulator, both stimulant/suppressive and stimulant. Icanbelimod has a monoisotopic molecular weight of 409.18 Da.

    Synonyms: S1p receptor agonist 1
  3. Drug

    Repaglinide

    go.drugbank.com/drugs/DB00912
    ApprovedInvestigational

    Meglitinides appear to be more effective at lowering postprandial blood glucose than metformin, sulfonylureas and thiazolidinediones.

    Mixtures: Repaglinide and Metformin Hydrochloride, Repaglinide and Metformin HydrochlorideCategories: metformin and repaglinide
  4. Drug

    KRN-633

    go.drugbank.com/drugs/DB33594
    Experimental

    Synonyms: Vegf receptor tyrosine kinase inhibitor iii
  5. Drug

    Nemolizumab

    go.drugbank.com/drugs/DB15252
    ApprovedInvestigational

    Nemolizumab is a humanized monoclonal modified immunoglobulin 2 (IgG2) antibody directed against interleukin-31 receptor alpha (IL-31RA),[L51159] which is an endogenous cytokine implicated in the pathophysiology

    Categories: Interleukin-31 Receptor alpha AntagonistSynonyms: Immunoglobulin G2, anti-(interleukin 31 receptor A) (human-Mus musculus monoclonal CIM331 γ-chain), disulfide with human-Mus musculus monoclonal CIM331 κ-chain, dimer, immunoglobulin G2-kappa, anti-[Homo sapiens IL31RA (interleukin 31 receptor subunit alpha)], humanized monoclonal antibody gamma2 heavy chain (1-445) [humanized VH (Homo sapiens IGHV1-2*02 (83.70%) -(IGHD
  6. Drug

    4A10

    go.drugbank.com/drugs/DB18292
    Experimental

    Synonyms: Anti-interleukin-7 Receptor α Monoclonal antibody
  7. Drug

    Prolactin G129R

    go.drugbank.com/drugs/DB18431
    Investigational

    Synonyms: Prolactin receptor antagonist (Prolactin G129R)
  8. Drug

    Sotatercept

    go.drugbank.com/drugs/DB12118
    ApprovedInvestigational

    It is a homodimeric recombinant fusion protein consisting of the extracellular domain of the human activin receptor type IIA (ActRIIA) linked to the human IgG1 Fc domain.

    Synonyms: ACTIVIN RECEPTOR TYPE IIA (SYNTHETIC HUMAN EXTRACELLULAR DOMAIN-CONTAINING FRAGMENT) FUSION PROTEIN WITH IMMUNOGLOBULIN G1 (SYNTHETIC HUMAN HEAVY CHAIN FC FRAGMENT), DIMER, (HUMAN ACTIVIN RECEPTOR TYPE-2A PRECURSOR-(21-135)-PEPTIDYL)-THREONYLTRIGLYCYL-(HUMAN IMMUNOGLOBULIN HEAVY CONSTANT .GAMMA.1 FC FRAGMENT: (8-15)-HINGE-(A-100>V)-CH2-CH3 OF HOMO SAPIENS IGHG1*03), (123-
  9. Drug

    Valziflocept

    go.drugbank.com/drugs/DB17728
    Investigational

    Synonyms: Recombinant human soluble fc-gamma receptor iib, Fc.gamma.riib receptor (human soluble extracellular fragment)
  10. Drug

    Sipavibart

    go.drugbank.com/drugs/DB21908
    ApprovedInvestigational

    [A274098] It works by binding to the SARS-CoV-2 spike protein receptor binding domain (RBD), neutralize the virus and preventing its entry into the host cell.

    Synonyms: Immunoglobulin G1-lambda, anti-[Homo sapiens severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) protein, receptor binding domain (RBD)], Homo sapiens monoclonal antibody, Immunoglobulin G1 [242-phenylalanine,243-glutamic acid,260-tyrosine,262-threonine,264-glutamic acid,339-serine], anti-(severe acute respiratory syndrome coronavirus 2 spike glycoprotein receptor-binding