Search
Fazpilodemab
go.drugbank.com/drugs/DB18924InvestigationalFazpilodemab is under investigation in clinical trial NCT04171765 (A Study to Evaluate the Efficacy, Safety, and Pharmacokinetics of BFKB8488A Compared With Placebo in Participants With Non-alcoholic Steatohepatitis
Synonyms: immunoglobulin G1-kappa, anti-[Homo sapiens KLB (klotho beta, b-Klotho)] and anti-[Homo sapiens FGFR1 (fibroblast growth factor receptor 1, FLT2, KAL2)], monoclonal antibody, bispecific; gamma1 heavy chain, 410-valine], anti-(human β-Klotho protein) (human monoclonal HKLB4206 γ1-chain), disulfide with monoclonal HKLB4206 κ-chain, (229→225'),(232→228')-bis(disulfide) with immunoglobulin G1 [365-tryptophan] antPolymyxin B
go.drugbank.com/drugs/DB00781ApprovedInvestigationalVet approvedPolymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic[A176426,FDA Label]. … It is appropriate for treatment of infections of the urinary tract, meninges, and blood stream, caused by susceptible strains of _Pseudomonas aeruginosa_[FDA Label].
Mixtures: Bus and Classroom Yellow, Care Bus and Classroom YellowCategories: Alimentary Tract and Metabolism, Amino Acids, Peptides, and ProteinsPrenylamine
go.drugbank.com/drugs/DB04825ApprovedWithdrawnPrenylamine was withdrawn from the Canadian, US, and UK markets in 1988 due to concerns regarding cardiac arrhythmias.
Synonyms: N-(3,3-Diphenylpropyl)-alpha-methylphenaethylamin, N-(3,3-Diphenylpropyl)-alpha-methylphenethylamineCategories: Calcium-Regulating Hormones and Agents, Vasodilators Used in Cardiac DiseasesAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigational[A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.
Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranInternational brands: Amio-Aqueous IVBenzocaine
go.drugbank.com/drugs/DB01086ApprovedInvestigationalBenzocaine is an ester local anesthetic that acts by preventing transmission of impulses along nerve fibers and at nerve endings. … [A231219] It is commonly used for local anesthesia in many over the counter products.[L32454,L32459,L32464] Benzocaine was first used for local anesthesia in dentistry.[A231259]
Mixtures: Bus and Classroom Yellow, Oti CalCategories: Antipruritics and Local Anesthetics, Agents for Treatment of Hemorrhoids and Anal Fissures for Topical UseFlurbiprofen
go.drugbank.com/drugs/DB00712ApprovedInvestigationalFlurbiprofen is structurally and pharmacologically related to fenoprofen, ibuprofen, and ketoprofen. … Flurbiprofen, a propionic acid derivative, is a nonsteroidal anti-inflammatory agent (NSAIA) with antipyretic and analgesic activity.
Mixtures: MAJEZIK DUO 100MG/8MG FILM KAPLI TABLET, TABLET, 14 ADETCategories: Antiinflammatory and Antirheumatic Products, Topical Products for Joint and Muscular PainClarithromycin
go.drugbank.com/drugs/DB01211ApprovedInvestigationalClarithromycin may be bacteriostatic or bactericidal depending on the organism and drug concentration. … Binding inhibits peptidyl transferase activity and interferes with amino acid translocation during the translation and protein assembly process.
Mixtures: HELIPAK 500 + 30 + 1000mg TEDAVİ PAKETİ, 7 TABLET, HELIPAK 500 + 30 + 1000mg TEDAVİ PAKETİ, 14 TABLETCategories: Alimentary Tract and Metabolism, Erythromycin and similarsAbemaciclib
go.drugbank.com/drugs/DB12001ApprovedInvestigationalAbemaciclib is an antitumor agent and dual inhibitor of cyclin-dependent kinases 4 (CDK4) and 6 (CDK6) that are involved in the cell cycle and promotion of cancer cell growth in case of unregulated activity … It is either given alone in patients who has undergone endocrine therapy and chemotherapy after the metastasis of cancer, or in combination with [DB00947].
Categories: Antineoplastic and Immunomodulating AgentsProducts: VERZENIO FILM-COATED TABLET 50MG, Yulareb 50mg film-coated tabletsDocetaxel
go.drugbank.com/drugs/DB01248ApprovedInvestigational[A259676] Compared to paclitaxel, docetaxel is two times more potent as an inhibitor of microtubule depolymerization. Docetaxel binds to microtubules but does not interact with dimeric tubulin. … [L46466] Docetaxel was approved by the FDA in 1996 and is available in solution for injection for intravenous or parenteral administration.[A259676]
Synonyms: N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetyltaxol, N-Debenzoyl-N-(tert-butoxycarbonyl)-10-deacetylpaclitaxelCategories: Antineoplastic and Immunomodulating AgentsOctocrylene
go.drugbank.com/drugs/DB09535ApprovedHowever, the use of this chemical doesn’t just stop with sunscreen for face and arms, but can extend to a variety of other products, like hair spray, tannin oil, BB cream, conditioner, and CC cream, among … What makes this chemical such a popular additive to sun block, is its ability to neutralize UV radiation dissipated by sunlight, and to minimize skin damage from prolonged sun exposure.
Mixtures: Your Skin But Better Cc+, Your Skin But Better Cc+ Nude GlowProducts: UV Defense Pocket Sun Pad (Broad Spectrum, SPF30), UV Defense Pocket Sun Block Tissues (Broad Spectrum, SPF30)