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Vildagliptin
go.drugbank.com/drugs/DB04876ApprovedInvestigational[A232488] Oral vildagliptin was approved by the European Medicines Agency in 2008 for the treatment of type II diabetes mellitus in adults as monotherapy or in combination with [metformin], a sulfonylurea … [L32813] Vildagliptin is currently under investigation in the US.
Mixtures: VILDAGLIPTIN E METFORMINA SANDOZ, VILDAGLIPTIN E METFORMINA SANDOZCategories: Drugs Used in DiabetesTamoxifen
go.drugbank.com/drugs/DB00675ApprovedInvestigational[A1025,L7799,L7802] Tamoxifen is used alone or as an adjuvant in these treatments. … [A1026] Tamoxifen was granted FDA approval on 30 December 1977.[L7799]
Synonyms: 1-p-beta-Dimethylaminoethoxyphenyl-trans-1,2-diphenylbut-1-ene, (Z)-2-(4-(1,2-Diphenyl-1-butenyl)phenoxy)-N,N-dimethylethanamineProducts: TAMOXIFENE EGMethotrexate
go.drugbank.com/drugs/DB00563ApprovedInvestigational[A180322,L7144,L7147,L7150,L7180] Due to the toxic effects of methotrexate, it is indicated for treatment of some forms of arthritis and severe psoriasis only if first line treatment has failed or patients … [L7180] Methotrexate was granted FDA approval on 7 December 1953.[L7198]
Synonyms: 4-amino-N(10)-methylpteroylglutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acidProducts: NORDIMET 10MG ILO I E FER, NORDIMET 15MG ILO I E FERRopinirole
go.drugbank.com/drugs/DB00268ApprovedInvestigationalIn 2005, it was the first drug approved in the US for the management of primary moderate to severe restless legs syndrome [A174547]. … Ropinirole was initially approved in 1997 by the FDA [FDA label] for the management of Parkinson's disease.
Products: ROPINIROLO EG, ROPINIROLO EG STADACapsaicin
go.drugbank.com/drugs/DB06774ApprovedInvestigationalCapsaicin is most often used as a topical analgesic and exists in many formulations of cream, liquid, and patch preparations of various strengths; however, it may also be found in some dietary supplements … Capsaicin is a naturally-occurring botanical irritant in chili peppers, synthetically derived for pharmaceutical formulations.
Synonyms: (E)-8-Methyl-N-vanillyl-6-nonenamide, trans-8-Methyl-N-vanillyl-6-nonenamideMixtures: NuDroxiPAK E-400, Trubrexa Patch ERCitalopram
go.drugbank.com/drugs/DB00215ApprovedInvestigational[A261316] Citalopram was approved by the FDA in 1998 for the treatment of depression in adults 18 years or older.[L5230] … Citalopram is an antidepressant belonging to the class of selective _serotonin-reuptake inhibitors_ (SSRIs) widely used to treat the symptoms of depression.
Products: CITALOPRAM EG, CITALOPRAM EG STADALansoprazole
go.drugbank.com/drugs/DB00448ApprovedInvestigational[A177065] It reduces gastric acid secretion by targeting gastric H,K-ATPase pumps and is thus effective at promoting healing in ulcerative diseases, and treating gastroesophageal reflux disease (GERD)
Products: LANSOPRAZOLO EG, LANSOPRAZOLO EG STADABetahistine
go.drugbank.com/drugs/DB06698ApprovedInvestigationalIt is thought to reduce symptoms through its actions on histamine receptors. … It is currently marketed in Canada by various companies, including Teva Pharmaceuticals.
Synonyms: N-methyl-2-pyridineethanamine, N-methyl-2-(2-pyridinyl)ethanamineProducts: BETAISTINA EG, BETAVERT N 8MGPhenytoin
go.drugbank.com/drugs/DB00252ApprovedInvestigationalVet approved[A189219,A35884] Both parenteral and oral formulations of phenytoin are available on the market.[A189219] … [A33595,A188832,A189219] Since it's introduction about 80 years ago, phenytoin has not only been established as an effective anti-epileptic, but has also been investigated for several other indications
Products: Phenytoin ERAmiodarone
go.drugbank.com/drugs/DB01118ApprovedInvestigational[A36817] Most known for its approved indication in life-threatening ventricular arrhythmias, it is also used off-label in the outpatient and inpatient setting for atrial fibrillation. … Amiodarone is a benzofuran derivative, anti-arrhythmic drug used commonly in a variety of settings.
Synonyms: 2-n-Butyl-3',5'-diiodo-4'-N-diethylaminoethoxy-3-benzoylbenzofuranProducts: AMIODARONE EG