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Displaying results 4991 - 5000 of 10000 in total

Drug
Perflenapent
go.drugbank.com/drugs/DB11625
ApprovedInvestigationalWithdrawn
Dodecafluoropentane is also known as perfluoropentane or perflenapent.
Categories: Compounds used in a research, industrial, or household setting, Diagnostic Uses of Chemicals
Drug
Taurochenodeoxycholic acid
go.drugbank.com/drugs/DB08833
Experimental
As a medication, taurochenodeoxycholic acid reduces cholesterol formation in the liver, and is likely used as a choleretic to increase the volume of bile secretion from the liver and as a cholagogue to … Taurochenodeoxycholic acid is an experimental drug that is normally produced in the liver. Its physiologic function is to emulsify lipids such as cholesterol in the bile.
Categories: Compounds used in a research, industrial, or household setting, Cytochrome P-450 Substrates
Drug
Fidaxomicin
go.drugbank.com/drugs/DB08874
ApprovedInvestigational
Fidaxomicin is a novel macrolide antibiotic used in the treatment of diarrhea caused by _Clostridioides_ (formerly _Clostridium_) _difficile_ in adult and pediatric patients over the age of 6 months. … [A190486] The approved indication of fidaxomicin was expanded by the FDA in January 2020 to include pediatric patients over the age of 6 months in the treatment population.[L11575]
Synonyms: Tiacumicin BCategories: P-glycoprotein substrates, Cytochrome P-450 CYP3A Inhibitors
Drug
PEG-uricase
go.drugbank.com/drugs/DB05321
Investigational
of severe, treatment-refractory gout in the United States in 2006. … PEG-uricase, a polyethylene glycol ("PEG") conjugate of recombinant porcine uricase (urate oxidase), which breaks down the uric acid deposits is being studied in Phase III clinical trials for the treatment
Categories: Compounds used in a research, industrial, or household setting
Drug
Ceftolozane
go.drugbank.com/drugs/DB09050
ApprovedInvestigational
[L6685] It was approved by the FDA in 2014 for use in combination with [Tazobactam] for the treatment of serious infections, such as intra-abdominal infections and complicated urinary tract infections. … The manufacturer of this drug is Cubist Pharmaceuticals.
Synonyms: (6R,7R)-3-([3-Amino-4-(2-aminoethylcarbamoylamino)-2-methylpyrazol-1-ium-1-yl]methyl)-7-([(2Z)-2-(5-amino-1,2,4-thiadiazol-3-yl)-2-(2-carboxypropan-2-yloxyimino)acetyl]amino)-8-oxo-5-thia-1-azabicyclo[, 4.2.0]oct-2-ene-2-carboxylateMixtures: ZERBAXA ® 1 G/0.5 G, ZERBAXA ® 1 G/0.5 G
Drug
Thonzonium
go.drugbank.com/drugs/DB09552
Approved
It is widely used as an additive to in ear and nasal drops to enhance dispersion and penetration of cellular debris and exudate, thereby promoting tissue contact of the administered medication. … A common pharmaceutical formulation of thonzonium bromide is cortisporin-TC ear drops. It is also reported that thonzonium also confers an antifungal property and antiresorptive effect on bone.
Mixtures: Coly-Mycin S, Coly-Mycin SCategories: Heterocyclic Compounds, 1-Ring
Drug
Influenza A virus A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (UV, formaldehyde inactivated)
go.drugbank.com/drugs/DB14560
ApprovedWithdrawn
Inactivated vaccines contain a virus particle that has been grown in media and then subsequently killed, or inactivated, through exposure to heat or chemicals such as formaldehyde 3. … In contrast, live vaccines are produced from "wild-type" or disease-causing viruses that have been attenuated, or weakened, through various laboratory techniques.
Synonyms: Influenza A virus A/Singapore/INFIMH-16-0019/2016 IVR-186 (H3N2) antigen (UV, formaldehyde inactivated)Mixtures: VAXİGRİP TETRA 0,5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR , 1 ADET, VAXİGRİP 0,5 ML IM/SC ENJEKSİYON İÇİN SÜSPANSİYON İÇEREN KULLANIMA HAZIR ENJEKTÖR , 10 ADET
Drug
Steviolbioside
go.drugbank.com/drugs/DB12434
ApprovedWithdrawn
Steviolbioside has been used in trials studying the treatment of HIV-1 Infection.
Categories: Compounds used in a research, industrial, or household setting
Drug
Andexanet alfa
go.drugbank.com/drugs/DB14562
Approved
It is marketed as Andexxa for intravenous injection or infusion and is indicated for the reversal of anticoagulation in combination with [rivaroxaban] and [apixaban] in cases of life-threatening or uncontrolled … Andexanet alfa is a recombinant human coagulation Factor Xa that promotes blood coagulation. It was developed by Portola Pharmaceuticals and was approved in in May 2018.
Synonyms: r-AntidoteCategories: Factor X
Drug
Equine Botulinum Neurotoxin F Immune FAB2
go.drugbank.com/drugs/DB13901
Approved
It is intravenously administered for the treatment of symptomatic botulism following documented or suspected exposure to botulinum neurotoxin serotypes F in adults and pediatric patients. … Equine Botulinum Neurotoxin F Immune FAB2 is composed of a mixture of immune globulin fragments purified from plasma of horses that were previously immunized with botulinum toxin serotype F.
Synonyms: Botulinum Neurotoxin F immune FAB2 (equine), BOTULINUM NEUROTOXIN F IMMUNE FAB2, EQUINE