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Displaying results 5001 - 5010 of 10000 in total
  1. Drug

    TAK-448

    go.drugbank.com/drugs/DB11975
    Investigational

    TAK-448 has been used in trials studying the treatment of Prostate Cancer, Low Testosterone, Prostatic Neoplasms, and Hypogonadotropic Hypogonadism.

  2. Target

    CCN family member 3

    go.drugbank.com/bio_entities/BE0001147
    TargetHumans

    Immediate-early protein playing a role in various cellular processes including proliferation, adhesion, migration, differentiation and survival (PubMed:12050162, PubMed:12695522, PubMed:15181016, PubMed:15611078, PubMed:21344378). Acts b...

    Synonyms: NOV, Protein NOV homolog
  3. Target

    NADP-dependent glyceraldehyde-3-phosphate dehydrogenase

    go.drugbank.com/bio_entities/BE0002717
    TargetStreptococcus mutans serotype c (strain ATCC 700610 / UA159)

    Synonyms: Non-phosphorylating glyceraldehyde 3-phosphate dehydrogenaseFunction: glyceraldehyde-3-phosphate dehydrogenase (NADP+) (non-phosphorylating) activity
  4. Target

    Alpha-actinin-1

    go.drugbank.com/bio_entities/BE0008968
    TargetHumans

    F-actin cross-linking protein which is thought to anchor actin to a variety of intracellular structures. Association with IGSF8 regulates the immune synapse formation and is required for efficient T-cell activation (PubMed:22689882)

    Synonyms: Non-muscle alpha-actinin-1
  5. Target

    P-type sodium-transporting ATPase4

    go.drugbank.com/bio_entities/BE0009185
    TargetPlasmodium falciparum (isolate 3D7)

    Sodium-exporting ATPase (PubMed:23414762, PubMed:29986883, PubMed:31311978, PubMed:36180431). Required for the extrusion of Na(+) from the intraerythrocytic parasites to maintain a low cytosolic concentration of Na(+) (PubMed:23414762, P...

    Synonyms: Non-SERCA-type Ca2+-transporting P-ATPase
  6. Drug

    Nafarelin

    go.drugbank.com/drugs/DB00666
    ApprovedInvestigational

    Nafarelin is a potent synthetic agonist of gonadotropin-releasing hormone with 3-(2-naphthyl)-D-alanine substitution at residue 6. Nafarelin has been used in the treatments of central precocious puberty and endometriosis.

  7. Drug

    Gestaclone

    go.drugbank.com/drugs/DB21090
    Experimental

    The usage of the INN stem '-clone' in the name indicates that Gestaclone is a hypnotic tranquillizer. Gestaclone has a monoisotopic molecular weight of 370.17 Da.

  8. Drug

    Betoxycaine

    go.drugbank.com/drugs/DB19475
    Experimental

    The usage of the INN stem '-caine' in the name indicates that Betoxycaine is a local anaesthetic. Betoxycaine has a monoisotopic molecular weight of 352.24 Da.

  9. Drug

    Motrazepam

    go.drugbank.com/drugs/DB19799
    Experimental

    The usage of the INN stem '-azepam' in the name indicates that Motrazepam is a diazepam derivative. Motrazepam has a monoisotopic molecular weight of 325.11 Da.

  10. Drug

    Oximonam

    go.drugbank.com/drugs/DB19915
    Experimental

    The usage of the INN stem '-monam' in the name indicates that Oximonam is a monobactam antibiotic. Oximonam has a monoisotopic molecular weight of 357.07 Da.