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Olutasidenib
go.drugbank.com/drugs/DB16267ApprovedInvestigationalOlutasidenib (FT-2102) is a selective and potent isocitrate dehydrogenase-1 (IDH1) inhibitor approved by the FDA in December 2022. It is indicated for the treatment of relapsed or refractory acute myeloid leukemia (AML) in patients with ...
Categories: Cytochrome P-450 CYP1A2 Inducers, P-glycoprotein inhibitorsAcetylcysteine zidrimer
go.drugbank.com/drugs/DB16496InvestigationalSynonyms: Dendrimer N-acetyl-cysteineBirch bark extract
go.drugbank.com/drugs/DB16536ApprovedInvestigationalBirch bark extract is rich in triterpenoids with beneficial biological and pharmacological activities. Some of the compounds identified in it include betulin, lupeol, betulinic acid, oleanolic acid, and erythrodiol. Birch bark extract is...
Categories: Cytochrome P-450 CYP2C8 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTisotumab vedotin
go.drugbank.com/drugs/DB16732ApprovedInvestigationalTisotumab vedotin is a tissue factor-directed antibody-drug conjugate (ADC) comprised of an anti-tissue factor (TF) human IgG1-kappa antibody conjugated to monomethyl auristatin E (MMAE), a microtubule-disrupting agent, via a protease-cl...
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesCinchonidine
go.drugbank.com/drugs/DB16831ExperimentalCategories: Cytochrome P-450 CYP2D6 Inhibitors, Cytochrome P-450 Enzyme InhibitorsTyrosol
go.drugbank.com/drugs/DB16855ExperimentalSynonyms: p-TyrosolCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2A6 SubstratesU-0126
go.drugbank.com/drugs/DB17060ExperimentalU-0126 is a direct inhibitor of the mitogen-activated protein-kinase kinase family members, MEK-1 and MEK-2.[A253162]
Salts: U-0126-EtOHNorclobazam
go.drugbank.com/drugs/DB17092InvestigationalSynonyms: N-desmethylclobazamCategories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2C19 Substrates