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Edivoxetine
go.drugbank.com/drugs/DB09184InvestigationalEdivoxetine is a drug which acts as a selective norepinephrine reuptake inhibitor and is currently under development by Eli Lilly for attention-deficit hyperactivity disorder (ADHD) and as an antidepressant … Edivoxetine failed to be approved for major depressive disorder after phase III clinical trials in 2012.
Lunacalcipol
go.drugbank.com/drugs/DB05024InvestigationalThis proprietary new drug is both a potent inhibitor of CYP24 (the enzyme responsible for the breakdown of vitamin D) and a potent activator of vitamin D signaling pathways.
Amolimogene bepiplasmid
go.drugbank.com/drugs/DB04904InvestigationalAmolimogene was biologically engineered as a targeted therapy for the treatment of cervical dysplasia.
Washed Microbiota Transplantation
go.drugbank.com/drugs/DB15745InvestigationalWashed microbiota preparation (WMT) involves a method wherein FMT is used, but the preparation undergoes microfiltration through an automatic purification system combined with repeated centrifugation and
Agalsidase beta
go.drugbank.com/drugs/DB00103ApprovedInvestigationalAgalsidase beta is a recombinant human α-galactosidase A similar to agalsidase alfa. While patients generally do not experience a clinically significant difference in outcomes between the two drugs, some patients may experience greater b...
Imidazole-4-carboxylic acid
go.drugbank.com/drugs/DB16194ExperimentalImidazole-4-carboxylic acid is under investigation in clinical trial NCT00583895 (Safety and Efficacy Study of Imcooh Cream in Patients Suffering From Moderate Atopic Dermatitis).
Mosapride
go.drugbank.com/drugs/DB11675InvestigationalMosapride is under investigation for the treatment and prevention of Postoperative Ileus and Gastric Peroral Endoscopic Pyloromyotomy (G-POEM). … Mosapride has been investigated for the treatment and diagnostic of Constipation, Type 2 Diabetes, Functional Dyspepsia, Functional Constipation, and Epigastric Pain Syndrome, among others.
Categories: Drugs for Functional Gastrointestinal DisordersALM201
go.drugbank.com/drugs/DB17206InvestigationalALM201 is an anti-angiogenic synthetic peptide identified from the endogenous human protein, FKBPL. It is being investigated in the treatment of various cancers.[A254556]
XL999
go.drugbank.com/drugs/DB05014InvestigationalXL999 induces a cell-cycle block by a mechanism distinct from those previously identified and exhibits broad antitumor activity in xenograft models. … XL999 has the potential to prevent tumor growth — both directly by a novel effect on tumor cell proliferation and indirectly through inhibition of the host angiogenic response.
Psilocybin
go.drugbank.com/drugs/DB11664InvestigationalPsilocybin has been investigated for the treatment of Anxiety and Stage IV Melanoma. In November, 2019, it was granted Breakthrough Therapy status by the FDA.