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MK-8189
go.drugbank.com/drugs/DB19153InvestigationalMK-8189 is under investigation in clinical trial NCT04624243 (Efficacy and Safety of MK-8189 in Participants With an Acute Episode of Schizophrenia (MK-8189-008)).
Synonyms: 4-PYRIMIDINAMINE, 2-METHYL-6-(((1S,2S)-2-(5-METHYL-2-PYRIDINYL)CYCLOPROPYL)METHOXY)-N-((5-METHYL-1,3,4-THIADIAZOL-2-YL)METHYL)-Phencyclidine
go.drugbank.com/drugs/DB03575ExperimentalIllicitA hallucinogen formerly used as a veterinary anesthetic, and briefly as a general anesthetic for humans. Phencyclidine is similar to ketamine in structure and in many of its effects. … Like ketamine, it can produce a dissociative state. It exerts its pharmacological action through inhibition of NMDA receptors (receptors, N-methyl-D-aspartate).
N,N'-diphenyl-1,4-phenylenediamine
go.drugbank.com/drugs/DB14192ApprovedSynonyms: N,N'-diphenyl-1,4-phenylenediamineCategories: Compounds used in a research, industrial, or household settingBentonite
go.drugbank.com/drugs/DB11306ApprovedWithdrawnCategories: Compounds used in a research, industrial, or household settingPenicillium glaucum
go.drugbank.com/drugs/DB14171ApprovedPenicillium glaucum allergenic extract is used in allergenic testing.
Categories: Non-Standardized Food Allergenic Extract, Non-Standardized Fungal Allergenic ExtractJB991
go.drugbank.com/drugs/DB05081ExperimentalJB991 is a cyclopentenone prostaglandin analogue intended for treatment of psoriasis. … In addition a closely related cyclopentenone prostaglandin analogue has been shown to exert marked anti-inflammatory effect in vivo in an animal model. The drug will be applied topically on the skin.
Metaraminol
go.drugbank.com/drugs/DB00610ApprovedIt has been used primarily as a vasoconstrictor in the treatment of hypotension. … An adrenergic agonist that acts predominantly at alpha adrenergic receptors and also stimulates the release of norepinephrine.
Aluminum chlorohydrex propylene glycol
go.drugbank.com/drugs/DB11208ApprovedIt is an antiperspirant active ingredient found in antiperspirant drug products for over-the-counter human use. … Aluminum chlorohydrex propylene glycol is a complex consisting of Aluminum Chorohydrate and propylene glycol (PG).
Selisistat
go.drugbank.com/drugs/DB13978InvestigationalEnhances p53 acetylation in response to DNA damaging agents. … Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3