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Displaying results 5051 - 5060 of 9333 in total
  1. Drug

    Solithromycin

    go.drugbank.com/drugs/DB09308
    Investigational

    Solithromycin is a ketolide antibiotic undergoing clinical development for the treatment of community-acquired pneumonia (CAP) and other infections.

  2. Drug

    XL844

    go.drugbank.com/drugs/DB05149
    Investigational

    XL844 is a potent inhibitor of the checkpoint kinases CHK1 and CHK2, which induce cell cycle arrest in response to a variety of DNA damaging agents. … XL844 is investigated for the use and treatment solid tumors. XL844 is a solid.

  3. Drug

    EGS21

    go.drugbank.com/drugs/DB05056
    Experimental

    EGS21(TM) is a beta-D-glucosylceramide (GC) compound. It is a potential therapeutic for treating immune mediated disorders. … drug in the treatment of various immune mediated diseases, such as Crohn's disease, hepatitis, non-alcoholic steatohepatitis (NASH) or fatty liver and HIV.

  4. Drug

    GT 389-255

    go.drugbank.com/drugs/DB05894
    Experimental

    It is expected to block fat absorption with fewer side effects than currently marketed lipase inhibitors. … Peptimmune’s lead product GT 389-255, is a novel lipase inhibitor and fat binding hydrogel polymer conjugate for the treatment of obesity which has completed single and multiple ascending dose (SAD and

  5. Drug

    Iprindole

    go.drugbank.com/drugs/DB13496
    Experimental

    Categories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome
  6. Drug

    Quingestanol

    go.drugbank.com/drugs/DB13685
    Experimental

    Categories: Sex Hormones and Modulators of the Genital System
  7. Drug

    Hydroxyprogesterone

    go.drugbank.com/drugs/DB14570
    Investigational

    Categories: Sex Hormones and Modulators of the Genital System
  8. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA top...

  9. Drug

    Totrombopag

    go.drugbank.com/drugs/DB05930
    Investigational

    , thus representing a significant problem in the treatment of cancer patients. … This drug is developed by GlaxoSmithKline and used to treat Thrombocytopenia.Thrombocytopenia (decreased platelet count) is a common side effect of many chemotherapies and can lead to uncontrolled bleeding

  10. Drug

    Spermine

    go.drugbank.com/drugs/DB00127
    InvestigationalNutraceutical

    Spermine is associated with nucleic acids, particularly in viruses, and is thought to stabilize the helical structure.