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Mitiglinide
go.drugbank.com/drugs/DB01252InvestigationalMitiglinide is a drug for the treatment of type 2 diabetes. It may stimulate insulin secretion in beta-cells by closing off ATP dependant potassium ion channels.
Categories: Drugs Used in Diabetes, Alimentary Tract and MetabolismEnoxacin
go.drugbank.com/drugs/DB00467ApprovedA broad-spectrum 6-fluoronaphthyridinone antibacterial agent (fluoroquinolones) structurally related to nalidixic acid.
Categories: Metabolic Side Effects of Drugs and Substances, Topoisomerase II InhibitorsHycanthone
go.drugbank.com/drugs/DB14061ExperimentalPotentially toxic, but effective antischistosomal agent, it is a metabolite of LUCANTHONE. Hycanthone was approved by the FDA in 1975 but is no longer used.
Nelutroctiv
go.drugbank.com/drugs/DB21554InvestigationalNelutroctiv is a small molecule drug. Nelutroctiv is under investigation in clinical trial NCT05662215 (A Single and Multiple Ascending Dose Study of CK-3828136 in Healthy Adult Participants).
Pramiracetam
go.drugbank.com/drugs/DB13247ApprovedPramiracetam has been studied for the use in Alzheimer's disease and as an adjunct treatment to restore cognitive functioning post-electroconvulsive therapy in severe depression [L5470]. … Pramiracetam has been previously approved in some eastern European countries under the brand names Pramistar, Neupramir, and Remen.
Categories: Psychostimulants, Agents Used for ADHD and NootropicsT-5224
go.drugbank.com/drugs/DB05998ExperimentalT-5224 is an investigational drug developed to treat Sepsis-induced Acute Kidney Injury. It's mechanism of action is to inhibit c-Fos/activator protein-1.
Eprotirome
go.drugbank.com/drugs/DB05035InvestigationalEprotirome which is a compound with promising properties for treatment of obesity and dyslipidemia. … Eprotirome increases the body’s energy consumption and reduces body weight and markedly reduces blood lipids and blood glucose.
PRO-542
go.drugbank.com/drugs/DB05793InvestigationalPRO 542 belongs to a new class of drugs, viral-entry inhibitor, which is intended to prevent HIV from entering and infecting cells. … PRO 542 (CD4-immunoglobulin G2) is a tetravalent CD4-immunoglobulin fusion protein that broadly neutralizes primary HIV-1 isolates.
Categories: Amino Acids, Peptides, and ProteinsREP8839
go.drugbank.com/drugs/DB05224ExperimentalREP8839 is a novel methionyl-tRNA synthetase (MetS) inhibitor being developed by Replidyne (GlaxoSmithKline licensed REP8839 to Replidyne in June of 2003).
Rhein
go.drugbank.com/drugs/DB13174ExperimentalRhein is an anthraquinone metabolite of rheinanthrone and senna glycoside is present in many medicinal plants including Rheum palmatum, Cassia tora, Polygonum multiflorum, and Aloe barbadensis [A19247] … It is known to have hepatoprotective, nephroprotective, anti-cancer, anti-inflammatory, and several other protective effects.