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Taste receptor type 2 member 3
go.drugbank.com/bio_entities/BE0023234TargetHumansGustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5
Polypeptides: Taste receptor type 2 member 3T cell receptor delta variable 2
go.drugbank.com/bio_entities/BE0023749TargetHumansV region of the variable domain of T cell receptor (TR) delta chain that participates in the antigen recognition (PubMed:24600447). Gamma-delta TRs recognize a variety of self and foreign non-peptide antigens frequently expressed at the ...
Polypeptides: T cell receptor delta variable 2Iomeprol
go.drugbank.com/drugs/DB11705ApprovedInvestigationalIomeprol is a tri-iodinated, non-ionic radiographic contrast agent for intraarterial or intravenous use. … [A265090,A265095] Iomeprol first appeared in the market in 1994 [A265095] and is currently used in various diagnostic processes involving x-ray imaging and computed tomography (CT) scans.[L52260]
Synonyms: N,N'-BIS(2,3-DIHYDROXYPROPYL)-2,4,6-TRIIODO-5-(N-METHYLGLYCOLAMIDO)ISOPHTHALAMIDE, 1,3-BENZENEDICARBOXAMIDE, N,N'-BIS(2,3-DIHYDROXYPROPYL)-5-((HYDROXYACETYL)METHYLAMINO)-2,4,6-TRIIODO-Categories: X-Ray Contrast Media, Iodinated, Compounds used in a research, industrial, or household settingDiazoxide
go.drugbank.com/drugs/DB01119ApprovedInvestigationalDiazoxide is a non-diuretic benzothiadiazine derivative that activates ATP-sensitive potassium channels. … In September 2015, the FDA issued a safety alert regarding post-marketing reports of pulmonary hypertension occurring in infants and neonates.
Categories: Heterocyclic Compounds, 2-Ring, Cytochrome P-450 SubstratesSynonyms: 7-chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxideTremelimumab
go.drugbank.com/drugs/DB11771ApprovedInvestigationalCTLA-4 is a cell surface receptor expressed on activated T cells to act as a negative regulator for T cells. … Tremelimumab, formerly known as ticilimumab, is a fully human IgG2 monoclonal antibody directed against cytotoxic T-lymphocyte-associated antigen 4 (CTLA-4).
Categories: CTLA-4-directed Blocking AntibodyProducts: Imjudo 25 mg/1.25 mL İnfüzyonluk Çözelti Hazırlamak İçin Konsantre, 1 adet, Imjudo Concentrate for Solution for Intravenous Infusion 20 mg/mLLarotrectinib
go.drugbank.com/drugs/DB14723ApprovedInvestigationalLarotrectinib is an orally administered inhibitor of tropomyosin receptor kinase (Trk), a receptor tyrosine kinase activated by neurotrophins which is mutated in a variety of cancer cell types and plays
Categories: P-glycoprotein substrates, Cytochrome P-450 SubstratesProducts: VITRAKVI 20 MG/ML ORAL ÇÖZELTİ, 2x50 ML, VITRAKVI 25 MG SERT KAPSÜL, 56 ADETAtomoxetine
go.drugbank.com/drugs/DB00289ApprovedInvestigationalMany contain a blackbox warning stating that CNS stimulants, including methylphenidate-containing products and amphetamines, have a high potential for abuse and dependence. … More recently, positron emission tomography (PET) imaging studies in rhesus monkeys have shown that atomoxetine also binds to the serotonin transporter (SERT),[A178111] and blocks the N-methyl-d-aspartate
Categories: Cytochrome P-450 Substrates, Cytochrome P-450 CYP2D6 SubstratesProducts: SETİNOX 5 MG KAPSÜL, 28 ADET, STRATTERA 25 MGMebeverine
go.drugbank.com/drugs/DB12554ApprovedInvestigationalWithdrawnMebeverine has been investigated for the treatment of Irritable Bowel Syndrome and Post-cholecystectomy Gastrointestinal Spasms.
Products: DUSPATALIN® 135 MG, DUSPATALIN® 135 MG TABLETAS RECUBIERTASZinc gluconate
go.drugbank.com/drugs/DB11248ApprovedInvestigationalVet approvedZinc gluconate is a zinc salt of gluconic acid comprised of two gluconic acid molecules for each zinc cation (2+). Zinc gluconate is a generally recognized as safe (GRAS) substance by FDA [L2081]. … It is available as a trace mineral supplement and over the counter as a lozenge form for a reduced duration of common colds and with decreased symptom severity.
Mixtures: AVi VITAMIN C 1000 mg with Zinc, Real Ginger, Honey, Lemon and Lemongrass, Super Daily No 2Products: Zink Aguettant 1 mg/ml Konzentrat zur Herstellung einer Infusionslösung, ZINC 50 MG.Fexofenadine
go.drugbank.com/drugs/DB00950ApprovedInvestigational[L4269] It is selective for the H<sub>1</sub> receptor, carries little-to-no activity at off-targets, and does not cross the blood-brain barrier[L10779] - this is in contrast to previous first-generation … [A1452] Fexofenadine is the major active metabolite of [terfenadine][A1495] and is administered as a racemic mixture in which both enantiomers display approximately equivalent antihistamine activity.
Synonyms: 4-(1-Hydroxy-4-(4-(hydroxydiphenylmethyl)-1-piperidinyl)butyl)-alpha,alpha-dimethylbenzeneacetic acidMixtures: Allegra-D 24 Hour, Allegra--D 24 Hour