Search

Displaying results 5061 - 5070 of 10000 in total
  1. Drug

    AdPEDF

    go.drugbank.com/drugs/DB05138
    Experimental

    AdPEDF is under development for the treatment of wet age-related macular degeneration (AMD). … It has been shown to rapidly elevate the intraocular AdPEDF protein levels in the eye, inhibit abnormal blood vessel growth, and cause abnormal blood vessels to regress while protecting the eye’s photoreceptors

  2. Drug

    AVAC

    go.drugbank.com/drugs/DB05441
    Experimental

    [Mycobacterium vaccae] is a non-pathogenic, saprophytic bacteria whose antigens can be used to induce peripheral immune activation through the activity of regulatory T-cells that surpress inappropriate … AVAC is derived from M. vaccae. It has been tested in uses related to asthma and in treating eczema and atopic dermatitis.

  3. Drug

    D-glyceraldehyde 3-phosphate

    go.drugbank.com/drugs/DB02263
    Experimental

    An aldotriose which is an important intermediate in glycolysis and in tryptophan biosynthesis.

  4. Drug

    XmAb 2513

    go.drugbank.com/drugs/DB06324
    Investigational

    It has been investigated for the treatment of hodgkin’s lymphoma. … XmAb 2513 is a humanized monoclonal antibody that targets the antigen CD30, a molecule expressed on the surface of a number of tumor cell types.

  5. Drug

    Daglutril

    go.drugbank.com/drugs/DB05796
    Investigational

    Daglutril is an orally active, mixed neutral endopeptidase/endothelin converting enzyme inhibitor under development for the treatment of essential hypertension and congestive heart failure.

  6. Drug

    Nebivolol

    go.drugbank.com/drugs/DB04861
    ApprovedInvestigational

    Nebivolol is a racemic mixture of 2 enantiomers where one is a beta adrenergic antagonist and the other acts as a cardiac stimulant without beta adrenergic activity. … [A182579] Treatment with nebivolol leads to a greater decrease in systolic and diastolic blood pressure than [atenolol], [propranolol], or [pindolol].

    Categories: Adrenergic beta-1 Receptor Agonists
  7. Drug

    Butyrfentanyl

    go.drugbank.com/drugs/DB09173
    ExperimentalIllicit

    [A182054] It is an analog of [fentanyl] with roughly 1/30 the potency.[L7811] Butyrfentanyl was first synthesized in 1961 by Janssen Pharmaceuticals as a new opioid analgesic. … [L7811] This compound is a schedule I controlled substance in the USA because it is a positional isomer of 3-Methylfentanyl.

  8. Drug

    Distearyldimonium

    go.drugbank.com/drugs/DB14143
    ApprovedWithdrawn

    Categories: Compounds used in a research, industrial, or household setting
  9. Drug

    Beractant

    go.drugbank.com/drugs/DB06761
    Approved

    It is suspended in 0.9% sodium chloride solution, and heat-sterilized. … Administration of lung surfactant remains the cornerstone of therapy in this condition that is currently the leading cause of death in preterm infants.

  10. Drug

    Crisaborole

    go.drugbank.com/drugs/DB05219
    ApprovedInvestigational

    It is currently under development as topical treatment of psoriasis. … This non-steroidal agent is efficacious in improving disease severity, reducing the risk of infection and reducing the signs and symptoms in patients 2 years old and older.