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IR501
go.drugbank.com/drugs/DB06464ExperimentalIR501 (Ravax) is a potential first-in-class vaccine for the treatment of Rheumatoid Arthritis. It specifically targets autoreactive T-cells, reducing their activity.
Adenosine-5'-Monophosphate Glucopyranosyl-Monophosphate Ester
go.drugbank.com/drugs/DB01774ExperimentalServes as the glycosyl donor for formation of bacterial glycogen, amylose in green algae, and amylopectin in higher plants. [PubChem]
Mibolerone
go.drugbank.com/drugs/DB11429ExperimentalVet approvedMibolerone is a potent anabolic steroid which is both higher affinity and more selective for the androgen receptor than metribolone.
Sibofimloc
go.drugbank.com/drugs/DB16400InvestigationalSibofimloc is under investigation in clinical trial NCT03943446 (TAK-018 for Prevention of the Recurrence of Postoperative Crohn's Disease (CD)).
SerpinPC
go.drugbank.com/drugs/DB17698InvestigationalSerpinPC is a mutated alpha-1-antitrypsin (α1AT) and serine protease inhibitor being investigated for the treatment of hemophilia.[A258993]
Etavopivat
go.drugbank.com/drugs/DB18176InvestigationalEtavopivat is a small molecule activator of erythrocyte pyruvate kinase (PKR) under investigation for the treatment of sickle cell disease.
CLBS12
go.drugbank.com/drugs/DB18192InvestigationalCLBS12 is a GCSF-mobilized autologous cell therapy derived from CD34+ cells being investigated for the treatment of Buerger’s disease.
Acapatamab
go.drugbank.com/drugs/DB18838InvestigationalAcapatamab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Zeluvalimab
go.drugbank.com/drugs/DB18868InvestigationalZeluvalimab is under investigation in clinical trial NCT04631601 (Safety and Efficacy of Therapies for Metastatic Castration-resistant Prostate Cancer (Mcrpc)).
Caficrestat
go.drugbank.com/drugs/DB15121InvestigationalAT-001 is under investigation in clinical trial NCT03062384 (AT-001 for Long-term Preservation of Brain Health in Aging).