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AP5280
go.drugbank.com/drugs/DB05112ExperimentalAP5280 is a novel N-(2-hydroxypropyl)methacrylamide (HPMA) copolymer-bound platinum (Pt) therapeutic designed to increase the therapeutic index relative to conventional, small-molecule platinum agents.
Vapreotide
go.drugbank.com/drugs/DB04894InvestigationalIt was being studied for the treatment of cancer.
Nalorphine
go.drugbank.com/drugs/DB11490ExperimentalVet approvedIt acts at two opioid receptors—at the mu receptor it has antagonistic effects, and at the kappa receptors it exerts high-efficacy agonistic characteristics. … It is used to reverse opioid overdose and (starting in the 1950s) in a challenge test to determine opioid dependence.
Categories: Heterocyclic Compounds with 4 or More RingsPocenbrodib
go.drugbank.com/drugs/DB21616InvestigationalPocenbrodib has a monoisotopic molecular weight of 525.23 Da. … Pocenbrodib is under investigation in clinical trial NCT06785636 (Open-Label Study of Pocenbrodib Alone and in Combination With Abiraterone Acetate, Olaparib, or 177Lu-PSMA-617).
Mevidalen
go.drugbank.com/drugs/DB19034InvestigationalMevidalen is under investigation in clinical trial NCT03305809 (A Study of LY3154207 in Participants With Dementia Due to Lewy Body Dementia (LBD) Associated With Idiopathic Parkinson's Disease (PD) or
Apramycin
go.drugbank.com/drugs/DB04626InvestigationalVet approvedIt is not approved for use in humans. … Apramycin is an aminoglycoside antibiotic and has a bactericidal action against many gram-negative bacteria.
Synonyms: 4-O-((8R)-2-amino-8-O-(4-amino-4-deoxy-α-D-glucopyranosyl)-2,3,7-trideoxy-7-(methylamino)-D-glycero-α-D-allo-octodialdo-1,5:8,4-dipyranos-1-yl)-2-deoxy-D-streptamine, 4-O-(3α-amino-6α-((4-amino-4-deoxy-α-D-glucopyranosyl)oxy)-2,3,4,5aβ,6,7,8,8aα-octahydro-8β-hydroxy-7β-(methylamino)pyrano(3,2-b)pyran-2α-yl)-2-deoxy-D-streptamineIprindole
go.drugbank.com/drugs/DB13496ExperimentalCategories: Serotonergic Drugs Shown to Increase Risk of Serotonin Syndrome, Non-Selective Monoamine Reuptake InhibitorsIdronoxil
go.drugbank.com/drugs/DB04915InvestigationalIdronoxil is a substance that is being studied in the treatment of cancer. It belongs to the family of drugs called signal transduction inhibitors.
Synonyms: 3-(4-hydroxyphenyl)-2H-chromen-7-ol, (+/-)-cis-3-(4-hydroxyphenyl)-4-(4-methoxyphenyl)-3,4-dihydro-2H-cromen-7-olOrgotein
go.drugbank.com/drugs/DB11444ExperimentalVet approvedSuperoxide dismutase (SOD) is an enzyme that alternately catalyzes the dismutation of the superoxide radical into either the less damaging hydrogen peroxide or molecular oxygen. … Superoxide is a natural byproduct of oxygen metabolism which, if left unchecked, leads to cell damage.
Categories: Analgesics, Non-Narcotic, Antiinflammatory and Antirheumatic Products, Non-SteroidsHydrogenobyrinic acid
go.drugbank.com/drugs/DB02460ExperimentalCategories: Heterocyclic Compounds with 4 or More Rings