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Displaying results 5091 - 5100 of 9333 in total
  1. Drug

    Aptazapine

    go.drugbank.com/drugs/DB09305
    Experimental

    Aptazapine (CGS-7525A) was a tetracyclic antidepressant developed in the 1980s. Aptazapine had noradrenergic and specific serotonergic activity.

  2. Drug

    Ulevostinag

    go.drugbank.com/drugs/DB14721
    Investigational

    factor-kappa B (NF-kB) and interferon regulatory factor 3 (IRF3) in immune cells in the tumor microenvironment; this leads to the production of pro-inflammatory cytokines, including interferons (IFNs) … Specifically, expression of IFN-beta (IFNb) enhances the cross-presentation of tumor-associated antigens by CD8alpha-positive and CD103-positive dendritic cells (DCs) to cytotoxic T lymphocytes (CTLs).

  3. Drug

    Sparfloxacin

    go.drugbank.com/drugs/DB01208
    ApprovedWithdrawn

    Sparfloxacin is a fluoroquinolone antibiotic indicated for bacterial infections. Sparfloxacin exerts its antibacterial activity by inhibiting DNA gyrase, a bacterial topoisomerase. DNA gyrase is an essential enzyme which controls DNA top...

  4. Drug

    5-deoxyflavanone

    go.drugbank.com/drugs/DB03601
    Experimental

    This compound belongs to the flavanones. … These are compounds containing a flavan-3-one moiety, whose structure is characterized by a 2-phenyl-3,4-dihydro-2H-1-benzopyran bearing a ketone at the carbon C3.

  5. Drug

    TC-5231

    go.drugbank.com/drugs/DB05333
    Experimental

    TC-5231 is mecamylamine hydrochloride, the active ingredient in FDA-approved product, Inversine, but in a lower dose than Inversine. … TC-5231 is a small molecule that has been under investigation as an oral treatment for ADHD (Attention Deficit/Hyperactivity Disorder).

  6. Drug

    2,6-dicarboxynaphthalene

    go.drugbank.com/drugs/DB08262
    Experimental

    This compound belongs to the naphthalenecarboxylic acids. These are compounds containing a napthalene moiety with a ring carbon which bears a carboxylic acid group. … This drug targets the proteins hemoglobin subunit alpha and hemoglobin subunit beta.

  7. Drug

    Calendula officinalis flower

    go.drugbank.com/drugs/DB14263
    Approved

    Calendula officinalis flower is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  8. Drug

    Rumex crispus whole

    go.drugbank.com/drugs/DB14267
    Approved

    Rumex crispus whole is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  9. Drug

    Ocimum tenuiflorum top

    go.drugbank.com/drugs/DB14273
    ApprovedWithdrawn

    Ocimum tenuiflorum top is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.

  10. Drug

    Kaempferia galanga root

    go.drugbank.com/drugs/DB14288
    ApprovedWithdrawn

    Kaempferia galanga root is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.