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Fucoxanthin
go.drugbank.com/drugs/DB15462Investigational, but the exact mechanism of anti-cancer action of fucoxanthin is not fully elucidated. … Fucoxanthin is under investigation in clinical trial NCT03613740 (Effect of Fucoxanthin on the Components of the Metabolic Syndrome, Insulin Sensitivity and Insulin Secretion).
Volanesorsen
go.drugbank.com/drugs/DB15067Approved[L16621] It is indicated to treat familial chylomicronemia, a genetic condition that prevents breakdown of triglycerides and chylomicrons.
Afelimomab
go.drugbank.com/drugs/DB04956ExperimentalAfelimomab (also known as Fab 2 or MAK 195F) is an anti-TNF-α monoclonal antibody. Administration of 195F reduces the concentration of interleukin-6 in patients with sepsis.
MM-093
go.drugbank.com/drugs/DB05512Investigationaltrimester of pregnancy. … Research on AFP suggests that it may play a role in modulating the immune system of the mother in order to protect the developing fetus during pregnancy.
LY2275796
go.drugbank.com/drugs/DB05165InvestigationalLY2275796 targets eukaryotic initiation factor- 4E (eIF-4E), a protein involved in the translation of key growth and survival factors that drive tumor progression, angiogenesis and metastases.
ORG-25935
go.drugbank.com/drugs/DB12220InvestigationalOrg 25935 has been used in trials studying the treatment of Alcoholism, Schizophrenia, and Panic Disorder.
Salts: Org 25935 HydrochlorideFusafungine
go.drugbank.com/drugs/DB08965ApprovedWithdrawnFusafungine is an antibiotic from Fusarium lateririum, and is used for the treatment of respiratory infections.
Leriglitazone
go.drugbank.com/drugs/DB15021InvestigationalLeriglitazone is under investigation in clinical trial NCT03917225 (A Clinical Study to Evaluate the Effect of MIN-102 on the Progression of Friedreich's Ataxia in Male and Female Patients).
LSZ-102
go.drugbank.com/drugs/DB15362InvestigationalLSZ-102 is under investigation in clinical trial NCT02734615 (Phase I/Ib Trial of LSZ102 Single Agent or LSZ102 + LEE011 or LSZ102 + BYL719 in ER+ Breast Cancers).
OSI-027
go.drugbank.com/drugs/DB12387InvestigationalOSI-027 has been used in trials studying the treatment of Any Solid Tumor or Lymphoma.