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KER-047
go.drugbank.com/drugs/DB19111InvestigationalKER-047 is under investigation in clinical trial NCT05927012 (A Study to Evaluate the Safety and Preliminary Efficacy of a Response-guided Dose Titration of KER-047 in the Treatment of Functional IDA (
N-[(2S,4S,6R)-2-(dihydroxymethyl)-4-hydroxy-3,3-dimethyl-7-oxo-4lambda~4~-thia-1-azabicyclo[3.2.0]hept-6-yl]-2-phenylacetamide
go.drugbank.com/drugs/DB08559ExperimentalThis compound belongs to the penicillins. … from the sulfur atom at position 1].
Denufosol
go.drugbank.com/drugs/DB04983InvestigationalThe drug was also evaluated in the treatment of retinal detachment and other diseases of the retina. Denufosol has not gained FDA approval, and clinical trials with this drug have ceased since 2011. … A new drug application (NDA) was filed with the FDA in 2011, however, the second phase III clinical trial showed a lack of improvement in lung function for cystic fibrosis patients taking denufosol.
Alvespimycin
go.drugbank.com/drugs/DB12442InvestigationalIn comparison to the first HSP90 inhibitor tanespimycin, it exhibits some pharmacologically desirable properties such as reduced metabolic liability, lower plasma protein binding, increased water solubility … It has been used in trials studying the treatment of solid tumor in various cancer as an antitumor agent.
ARX201
go.drugbank.com/drugs/DB05082InvestigationalARX201 (PEG-ahGH) is a recombinant form of human growth hormone that has been modified using Ambrx’s patented ReCODE™ technology to achieve precise spatial positioning of the site of polyethylene glycol … (PEG) attachment to human growth hormone, by biosynthetic incorporation of a chemically unique amino acid (ahGH).
Oglufanide
go.drugbank.com/drugs/DB05779InvestigationalOglufanide works as a regulator of the body's immune response, is being given by intranasal administration to patients with chronic hepatitis C viral infection. … Oglufanide was originally developed to treat severe infectious disease in Russia (where it is a registered pharmaceutical), and was extensively studied in cancer clinical trials in the United States before
Indian frankincense
go.drugbank.com/drugs/DB14275ApprovedInvestigationalIndian frankincense is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Shea butter
go.drugbank.com/drugs/DB14311ApprovedShea butter is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Usnea barbata
go.drugbank.com/drugs/DB14351ApprovedUsnea barbata is a plant/plant extract used in some OTC (over-the-counter) products. It is not an approved drug.
Terizidone
go.drugbank.com/drugs/DB12954ApprovedInvestigationalWithdrawnTerizidone has been used in trials studying the treatment of Tuberculosis, HIV Infections, Multidrug Resistant Tuberculosis, and Extensively-drug Resistant Tuberculosis.