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Displaying results 5111 - 5120 of 10000 in total
  1. Drug

    Cyclotheonamide A

    go.drugbank.com/drugs/DB04269
    Experimental

    Cyclotheonamide A is a cyclic peptide isolated from the marine sponge Theonella.

    Categories: Amino Acids, Peptides, and Proteins
  2. Drug

    FavId

    go.drugbank.com/drugs/DB05249
    Investigational

    FavId, is an active immunotherapy that is based upon unique genetic information extracted from a patient's tumor.

  3. Drug

    NNZ-2591

    go.drugbank.com/drugs/DB15601
    Investigational

    It was granted Orphan Drug Designation by the FDA in October 2019[L11103] and was granted a patent by the European Patent Office in December 2019. … [L11106] It is currently under development by Neuren Pharmaceuticals for the symptomatic treatment of Angelman, Phelan-McDermid, and Pitt Hopkins Syndromes.

    Categories: Amino Acids, Peptides, and Proteins
  4. Drug

    ABT-510

    go.drugbank.com/drugs/DB05434
    Investigational

    It is developed by Abbott Laboratories for the treatment of Solid Tumors, Lymphoma and Melanoma. … ABT-510 is a peptide mimetic of thrombospondin-1 (TSP-1), blocks angiogenesis in vitro and in vivo, and slows tumor growth.

    Categories: Amino Acids, Peptides, and Proteins
  5. Drug

    BacTRL-spike

    go.drugbank.com/drugs/DB15811
    Investigational

    BacTRL-Spike is composed of a bacterial medium with colony-forming-units of live Bifidobacterium longum engineered to deliver synthetic DNA encoding spike protein from SARS-CoV-2 contained by plasmids. … As of June, 2020, the company is pursuing a Phase 1, Randomized, Observer-Blind, Placebo-Controlled Trial (NCT04334980) to test the safety and immunogenicity of the vaccine.

  6. Drug

    Quinethazone

    go.drugbank.com/drugs/DB01325
    Approved

    Patients may experience adverse reactions such as dizziness, dry mouth, nausea, and hypokalemia.

    Categories: quinethazone and potassium, Genito Urinary System and Sex Hormones
  7. Drug

    XL228

    go.drugbank.com/drugs/DB05184
    Investigational

    , survival and metastasis. … XL228 is a novel anticancer compound designed to inhibit the insulin-like growth factor type-1 receptor (IGF1R), Src and Abl tyrosine kinases – targets that play crucial roles in cancer cell proliferation

  8. Drug

    TM5614

    go.drugbank.com/drugs/DB16516
    Investigational

    PAI-1 is a marker of obesity, type 2 diabetes, and metabolic syndrome[L31673,A228793,A228798], and current studies are exploring downstream effects of its inhibition. … An animal study in mice fed a fast-food diet with TM5614 treatment showed improved metabolic measurements and reduced liver steatosis[L31673,L31678].

  9. Drug

    Uracil mustard

    go.drugbank.com/drugs/DB00791
    Approved

    It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage.

    Categories: Antineoplastic and Immunomodulating Agents
  10. Drug

    Besifovir dipivoxil

    go.drugbank.com/drugs/DB05020
    Investigational

    The HBV polymerase is the enzyme that catalyzes the production of new RNA from the existing strand of RNA. … Besifovir dipivoxil is believed to inhibit viral proliferation by interrupting the replicating machinery of the virus.