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Displaying results 5131 - 5140 of 10000 in total
  1. Drug

    Ciglitazone

    go.drugbank.com/drugs/DB09201
    Experimental

    Ciglitazone is a potent and selective PPARγ ligand with an EC50 of 3.0 µM. It is also an anti-hyperglycemic agent in the ob/ob murine model in vivo. … Ciglitazone significantly decreases VEGF production by human granulosa cells in an in vitro study, and may potentially be used in ovarian hyperstimulation syndrome.

  2. Drug

    Ioglycamic acid

    go.drugbank.com/drugs/DB13741
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  3. Drug

    Iopentol

    go.drugbank.com/drugs/DB13861
    Experimental

    Iopentol is used as a contrast medium.

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Simendan

    go.drugbank.com/drugs/DB12286
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  5. Drug

    Iobenzamic acid

    go.drugbank.com/drugs/DB13428
    Experimental

    Categories: Compounds used in a research, industrial, or household setting
  6. Drug

    Sampatrilat

    go.drugbank.com/drugs/DB21283
    Experimental

    Sampatrilat is a small molecule drug. Sampatrilat has a monoisotopic molecular weight of 584.25 Da.

    Categories: Agents Acting on the Renin-Angiotensin System
  7. Drug

    XL784

    go.drugbank.com/drugs/DB04991
    Investigational

    XL784 is a potent inhibitor of the ADAM-10 metalloprotease enzyme, a target of significant interest because of its important role in blood vessel formation and cell proliferation. … XL784 was specifically optimized to be MMP-1 sparing, thus potentially enhancing its safety profile and enabling higher dosing compared with other previously studied metalloprotease inhibitors.

  8. Drug

    Avexitide

    go.drugbank.com/drugs/DB14806
    ApprovedInvestigationalWithdrawn

    Avexitide is under investigation in clinical trial NCT02996812 (Evaluation of Single Ascending Doses of Subcutaneous Exendin 9-39 in Patients With Post-Bariatric Hypoglycemia).

  9. Drug

    Recombinant SARS-CoV-2 Vaccine (Sf9 Cell)

    go.drugbank.com/drugs/DB16443
    Investigational

    It also provided protection in non-human primates to an in vivo challenge with SARS-CoV-2[A226853]. … In pre-clinical trial testing on mice, rabbits, and non-human primates, the candidate was able to induce a functional antibody response within 7-14 days of initial injection[A226853].

  10. Drug

    Sulfameter

    go.drugbank.com/drugs/DB06821
    Approved

    Long acting sulfonamide used in leprosy, urinary, and respiratory tract infections.