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Displaying results 5131 - 5140 of 10000 in total
  1. Drug

    Procainamide

    go.drugbank.com/drugs/DB01035
    Approved

    A derivative of procaine with less CNS action.

    Categories: MATE 1 Substrates with a Narrow Therapeutic Index, MATE 2 Substrates with a Narrow Therapeutic IndexSynonyms: p-Amino-N-(2-diethylaminoethyl)benzamide, p-Aminobenzoic diethylaminoethylamide
  2. Drug

    Ritiometan

    go.drugbank.com/drugs/DB13267
    Approved

    Ritiometan is a nasal spray which is marketed by the name Nécyrane in France. It is indicated for use in viral rhinitis/ the common cold.

  3. Drug

    Rocaglamide

    go.drugbank.com/drugs/DB15495
    Experimental

    Rocaglamide, also referred to as rocaglamide-A, is the eponymous member of a class of anti-cancer phytochemicals known as rocaglamides. … [A186760] Rocaglamides are secondary metabolites of the plant genus _Aglaia_, and extracts of the plant have traditionally been used as a form of insect repellant due to its natural insecticidal properties

    Categories: Heterocyclic Compounds, 2-Ring
  4. Drug

    Cefovecin

    go.drugbank.com/drugs/DB11505
    ExperimentalVet approved

    It is used for the treatment of skin infections caused by Pasturella multocida in cats, and Staphylococcus intermedius/S. canis in dogs. … The presence of low concentrations of antibiotics is related to the development of microbial resistance.

    Categories: Heterocyclic Compounds, 2-Ring
  5. Drug

    Sovateltide

    go.drugbank.com/drugs/DB06138
    Investigational

    It is being developed as an adjunct to chemotherapy. … SPI-1620 is an endothelin B receptor agonist. In animal models SPI-1620 selectively and transiently increases tumor blood flow allowing increased delivery of anticancer agents to the tumor.

  6. Drug

    Maplirpacept

    go.drugbank.com/drugs/DB18441
    Investigational

    Maplirpacept is a recombinant fusion protein consisting of the CD47-binding domain of human signal regulatory protein alpha (SIRPa) linked to the IgG4 Fc region of human IgG.

    Synonyms: 1-118-Signal regulatory protein α (human) fusion protein with immunoglobulin G4 [128-proline] (human γ4-chain C region C-terminal fragment), dimer
  7. Drug

    AZD3409

    go.drugbank.com/drugs/DB04893
    Experimental

    As of February 2007 the development of AZD3409 had been discontinued. … AZD3409 is a farnesyl-transferase inhibitor (FAR) indicated for the treatment of solid tumors. Phase I trials were initiated January 2003, and were ongoing as of February 2004.

    Categories: Heterocyclic Compounds, 1-Ring
  8. Drug

    Lancovutide

    go.drugbank.com/drugs/DB05029
    Investigational

    Lancovutide is a 19-amino-acid tetracyclic peptide produced by Streptoverticillium cinnamoneus and is closely related to cinnamycin (Ro09-0198). It belongs to the lantibiotics. … Lancovutide, a peptide antibiotic, is in clinical development for the treatment of cystic fibrosis.

  9. Drug

    Levocabastine

    go.drugbank.com/drugs/DB01106
    Approved

    Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis. Levocabastine was discovered at Janssen Pharmaceutica in 1979.

    Categories: Heterocyclic Compounds, 1-Ring
  10. Drug

    Cathinone

    go.drugbank.com/drugs/DB01560
    ExperimentalIllicit

    Other amphetamines to share this structure include the antidepressant bupropion and the stimulant methcathinone, among others. Internationally, cathinone is categorized as a Schedule I drug. … Cathinone is a monoamine alkaloid found in the shrub Catha edulis (Khat).

    Synonyms: D-Cathinone