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Navitoclax
go.drugbank.com/drugs/DB12340InvestigationalNavitoclax is an orally bioavailable small molecule inhibitor of Bcl-2 family proteins. It is a substance being studied in the treatment of lymphomas and other types of cancer.
AG-702
go.drugbank.com/drugs/DB05836ExperimentalThis drug is developed by antigenics for the treatment of genital herpes infection and is under phase I of clinical trial.
RC118
go.drugbank.com/drugs/DB18428InvestigationalRC118 is an antibody-drug conjugate that consists of a recombinant humanized IgG1 anti-Claudin18.2 monoclonal antibody conjugated to MMAE.
AT-GTX-502
go.drugbank.com/drugs/DB17001ExperimentalAT-GTX-502 is an experimental, one-time gene therapy that uses AAV9 to deliver a functional copy of CLN3.
Doxapram
go.drugbank.com/drugs/DB00561ApprovedInvestigationalVet approvedA central respiratory stimulant with a brief duration of action. (From Martindale, The Extra Pharmocopoeia, 30th ed, p1225)
BMS-986251
go.drugbank.com/drugs/DB19007InvestigationalBMS-986251 is under investigation in clinical trial NCT03329885 (A Study of Experimental Medication BMS-986251, Taken by Mouth, in Healthy Participants and Patients With Average to Very Serious Psoriasis
Nezastomig
go.drugbank.com/drugs/DB19061InvestigationalNezastomig is under investigation in clinical trial NCT06085664 (A Pilot Presurgical Trial of REGN5678 (Anti-psma X CD28) in Patients With High-risk, Localized Prostate Cancer Followed by Radical Prostatectomy
QL1706
go.drugbank.com/drugs/DB17562InvestigationalQL1706 is an investigational bifunctional antibody that combines the activity of both PD-1 and CTLA-4 antibodies.
OptPA
go.drugbank.com/drugs/DB18325ExperimentalOptimized tPA (OptPA; W253R/R275S-tPA) is an engineered variant of tPA designed to exhibit reduced neurotoxicity.[A261486]