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Displaying results 511 - 520 of 10000 in total
  1. Drug

    Tofersen

    go.drugbank.com/drugs/DB14782
    ApprovedInvestigational

    [L46133] Continual FDA approval is contingent on clinical benefits from ongoing trials, particularly the Phase 3 ATLAST study in people with presymptomatic SOD1-ALS. … [L46108] Although there were various causes of ALS, 2% of ALS cases are due to SOD1 mutations, with more than 200 SOD1 mutations documented.

    Synonyms: DNA, D((2'-O-(2-METHOXYETHYL))M5RC-SP-(2'-O-(2-METHOXYETHYL))RA-(2'-O-(2-METHOXYETHYL))RG-SP-(2'-O-(2-METHOXYETHYL))RG-(2'-O-(2-METHOXYETHYL))RA-SP-T-SP-A-SP-M5C-SP-A-SP-T-SP-T-SP-T-SP-M5C-SP-T-SP-A-SP, -(2'-O-(2-METHOXYETHYL))M5RC-(2'-O-(2-METHOXYETHYL))R
  2. Drug

    Alendronic acid

    go.drugbank.com/drugs/DB00630
    ApprovedInvestigational

    Alendronic acid is a second generation bisphosphonate that is used for the treatment of some forms of osteoperosis and Paget's disease[FDA Label][A959,A203111].

    Mixtures: OSSOFORTIN A 70 MG+1200 MG/800 IU TEDAVİ PAKETİ, 4+24 ADET, BONMEGA 70 MG/2800 IU+1000 MG TEDAVI PAKETI, 4+24 ADETSynonyms: (4-amino-1-hydroxybutylidene)bisphosphonic acid, 4-amino-1-hydroxybutane-1,1-diphosphonic acid
  3. Drug

    IDM-4

    go.drugbank.com/drugs/DB05438
    Experimental

    IDM-4 is an immuno-designed molecule that completed phase I/II of investigation for the treatment of Leukemia. … It is a monoclonal antibody-specific antigen that can selectively target cancer-affected cells by coupling with tumor cell-killing MAK cells, which are derived from the patient's own monocytes.

    Synonyms: IDM-4
  4. Drug

    GsMtx-4

    go.drugbank.com/drugs/DB17861
    Investigational

    GsMtx-4 is a peptide found in tarantula venom that inhibits mechanosensitive ion channel (MSC) activity.

  5. Drug

    Iptacopan

    go.drugbank.com/drugs/DB16200
    ApprovedInvestigational

    Iptacopan is a small-molecule factor B inhibitor previously investigated as a potential treatment for the rare blood disease paroxysmal nocturnal hemoglobinuria (PNH) by inhibiting the complement factor … [A262566] Factor B is a positive regulator of the alternative complement pathway, where it activates C3 convertase and subsequently C5 convertase.

    Categories: Compounds used in a research, industrial, or household setting, Complement Factor B InhibitorSynonyms: 4-((2S,4S)-4-ethoxy-1-((5-methoxy-7-methyl-1H-indol-4-yl)methyl)piperidin-2-yl) benzoic acid, BENZOIC ACID, 4-((2S,4S)-4-ETHOXY-1-((5-METHOXY-7-METHYL-1H-INDOL-4-YL)METHYL)-2-PIPERIDINYL)-
  6. Drug

    4-isothioureidobutyronitrile

    go.drugbank.com/drugs/DB13010
    Investigational

    Thioureidobutyronitrile has been used in trials studying the treatment of Solid Tumors and Ovarian cancer.

  7. Drug

    4-Androstenediol

    go.drugbank.com/drugs/DB01526
    ExperimentalIllicit

    Synonyms: 4-Androstenediol
  8. Drug

    4-Iodopyrazole

    go.drugbank.com/drugs/DB02721
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 4-Iodopyrazole
  9. Drug

    4-Fluorobenzylamine

    go.drugbank.com/drugs/DB03243
    Experimental

    Synonyms: 4-Fluorobenzylamine
  10. Drug

    4-Fluorotryptophane

    go.drugbank.com/drugs/DB03386
    Experimental

    Synonyms: 4-Fluorotryptophane