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Displaying results 511 - 520 of 10000 in total
  1. Drug

    Vinflunine

    go.drugbank.com/drugs/DB11641
    ApprovedInvestigational

    While these patients have a median survival of approximately 4 months and a poor prognosis [L1396], there is currently no standard therapy in patients with advanced urothelial carcinoma [A32626]. … Like other vinca agents, vinflunine is an anti-mitotic agent that induces a cell cycle arrest at the G2/M phase and promotes cell death via apoptosis [L1396].

    Categories: P-glycoprotein substrates with a Narrow Therapeutic Index, Cytochrome P-450 CYP3A4 Substrates with a Narrow Therapeutic IndexSynonyms: 20',20'-difluoro-3',4'-dihydrovinorelbine, 4'-deoxy-20',20'-difluoro-5'-norvincaleukoblastine
  2. Drug

    USL-311

    go.drugbank.com/drugs/DB15265
    Investigational

    USL-311 is under investigation in clinical trial NCT02765165 (Phase 1/2 Study of USL311 Alone and in Combination With Lomustine in Subjects With Advanced Solid Tumors and Relapsed/Recurrent Glioblastoma

    Synonyms: 6-[4-(1-propan-2-ylpiperidin-4-yl)-1,4-diazepan-1-yl]-N-pyridin-4-ylpyridine-2-carboxamide, 2-Pyridinecarboxamide, 6-(hexahydro-4-(1-(1-methylethyl)-4-piperidinyl)-1H-1,4-diazepin-1-yl)-N-4-pyridinyl-
  3. Drug

    Dalosirvat

    go.drugbank.com/drugs/DB18960
    Investigational

    Dalosirvat is under investigation in clinical trial NCT03742518 (A Study Evaluating the Efficacy and Safety of SM04554 Topical Solution in Male Subjects With Androgenetic Alopecia).

    Synonyms: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-4-phenyl-butane-1,4-dione, 1-(2,3-dihydro-benzo(1,4)dioxin-6-yl)-4-phenyl-butane-1,4-dione
  4. Drug

    6-aza uridine 5'-monophosphate

    go.drugbank.com/drugs/DB03718
    Experimental

    Categories: Heterocyclic Compounds, 1-RingSynonyms: 6-Aza-UMP, 6-aza uridine 5'-monophosphate
  5. Drug

    beta-D-glucose 6-phosphate

    go.drugbank.com/drugs/DB04122
    Experimental

    Synonyms: 6-O-phosphono-β-D-glucopyranose, β-D-glucose 6-phosphate
  6. Drug

    4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL

    go.drugbank.com/drugs/DB06937
    Experimental

    Synonyms: 4-(6-HYDROXY-BENZO[D]ISOXAZOL-3-YL)BENZENE-1,3-DIOL
  7. Drug

    5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine

    go.drugbank.com/drugs/DB02004
    Experimental

    Synonyms: 5-(Aminomethyl)-6-(2,4-Dichlorophenyl)-2-(3,5-Dimethoxyphenyl)Pyrimidin-4-Amine
  8. Drug

    3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine

    go.drugbank.com/drugs/DB03631
    Experimental

    Synonyms: 3-(4-hydroxy-3-imino-6-oxo-cyclohexa-1,4-dienyl)-alanine
  9. Drug

    4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE

    go.drugbank.com/drugs/DB08016
    Experimental

    Synonyms: 4-(6-CHLORO-2,4-DIOXO-1,2,3,4-TETRAHYDROPYRIMIDIN-5-YL) BUTYL PHOSPHATE
  10. Drug

    6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one

    go.drugbank.com/drugs/DB08379
    Experimental

    Synonyms: 6-(4-chloro-2-fluoro-3-phenoxybenzyl)pyridazin-3(2H)-one