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Displaying results 5191 - 5200 of 10000 in total
  1. Drug

    Osoresnontrine

    go.drugbank.com/drugs/DB16274
    Investigational

    Osoresnontrine is under investigation in clinical trial NCT02281773 (A Study to Investigate the Efficacy, Safety and Tolerability of Four Different Doses of BI 409306 Compared to Placebo Given for 12 Weeks … in Patients With Schizophrenia on Stable Antipsychotic Treatment.).

  2. Drug

    Talizumab

    go.drugbank.com/drugs/DB05797
    Experimental

    TNX-901 is a therapeutic monoclonal antibodies designed to address significant unmet medical needs in the areas of asthma, allergy, inflammation and other diseases affecting the human immune system.

  3. Drug

    CCR5 mAb

    go.drugbank.com/drugs/DB05906
    Experimental

    CCR5 mAb is a fully human monoclonal antibody that specifically recognizes and binds the chemokine receptor CCR5, which is known to be a key facilitator of infection with human immunodeficiency virus ( … It was generated by HGS using the Abgenix XenoMouse technology.

  4. Drug

    Solenopsis richteri

    go.drugbank.com/drugs/DB11026
    Approved

    Solenopsis richteri allergenic extract is used in allergenic testing. It is extracted from the black imported fire ant which is native to South Amercia. … The species has also been introduced in North Amercia. When stung, the bites are characterized by sterile pustules that are surrounded by reddened swelling along with redness extending beyond.

    Categories: Non-Standardized Insect Venom Allergenic Extract
  5. Drug

    Nimacimab

    go.drugbank.com/drugs/DB15115
    Investigational

    Nimacimab is under investigation in clinical trial NCT03261739 (Safety Tolerability, and PK of RYI-018 After Repeat Dosing in Subjects With Non-Alcoholic Fatty Liver Disease (NAFLD)).

  6. Drug

    Phosmet

    go.drugbank.com/drugs/DB11448
    ExperimentalVet approved

    Phosmet is a phthalimide-derived organophosphate. It is a non-specific insecticide. It is mainly used on apple trees to control codling moths. … It is also used on other fruit crops, ornamentals, and vines to control aphids, suckers, mites, and fruit flies.

    Categories: Compounds used in a research, industrial, or household settingSynonyms: O,O-Dimethyl phthalimidomethyl phosphorodithioate, O,O-Dimethyl S-(phthalimidomethyl) dithiophosphate
  7. Drug

    Bavituximab

    go.drugbank.com/drugs/DB05136
    Investigational

    It binds to phosphatidylserine and other exposed host cell lipids when induced by cellular stress. Additional analogs in the class include 3G4, 2aG4, 9d2 and Hu3g4. … Bavituximab is a chimeric Anti-PS monoclonal antibody analog which is used to potentially treat cancers and viral infections.

  8. Drug

    CY-1503

    go.drugbank.com/drugs/DB17605
    Investigational

    It was investigated in cardiopulmonary bypass during surgical repair of congenital heart lesions. … CY-1503 is a pentasaccharide ethyl glycoside consisting of one alpha-D-sialylosyl residue as a sodium salt, two beta-D-galactopyranosyl residues, one 2-acetamido-beta-Dglucopyranosyl unit, and one alpha-L-fucopyranosyl

  9. Drug

    FK352B

    go.drugbank.com/drugs/DB06484
    Experimental

    FK352B is a adenosine A1 antagonist that is developed for the treatment of dialysis-induced hypotension.

  10. Drug

    UCB7362

    go.drugbank.com/drugs/DB17096
    Experimental

    UCB7362 is an orally active plasmepsin X (PMX) inhibitor currently investigated for the treatment of malaria. … [A254222] Plasmepsins are aspartyl proteases produced by the malaria parasite _Plasmodium falciparum_, and PMX is considered to be essential for parasite egress and invasion.