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Displaying results 5201 - 5210 of 8974 in total
  1. Drug

    Selisistat

    go.drugbank.com/drugs/DB13978
    Investigational

    Enhances p53 acetylation in response to DNA damaging agents. … Selective inhibitor of SIRT1 that does not inhibit histone deacetylase (HDAC) or other sirtuin deacetylase family members (IC50 values are 98, 19600, 48700, > 100000 and > 100000 nM for SIRT1, SIRT2, SIRT3

  2. Drug

    Lazuvapagon

    go.drugbank.com/drugs/DB19046
    Investigational

    Lazuvapagon is under investigation in clinical trial NCT03116191 (Trial of SK-1404 for Nocturia Due to Nocturnal Polyuria in Japanese Subjects).

  3. Drug

    Oxalic Acid

    go.drugbank.com/drugs/DB03902
    Experimental

    It is produced in the body by metabolism of glyoxylic acid or ascorbic acid. It is not metabolized but excreted in the urine. It is used as an analytical reagent and general reducing agent. [PubChem]

    Categories: Compounds used in a research, industrial, or household setting
  4. Drug

    Kinetin

    go.drugbank.com/drugs/DB11336
    Approved

    It was shown to naturally exist in DNA of organisms including humans and various plants. … While kinetin is used in tissue cultures to produce new plants, it is also found in cosmetic products as an anti-aging agents.

  5. Drug

    VX-148

    go.drugbank.com/drugs/DB06103
    Experimental

    VX-148 is a developed for the treatment of autoimmune diseases.

  6. Drug

    Etofenamate

    go.drugbank.com/drugs/DB08984
    Investigational

    Etofenamate is used to treat muscle and joint paint. It is a non-steroidal anti-inflammatory drug (NSAID).

    Categories: Topical Products for Joint and Muscular Pain, Antiinflammatory Preparations, Non-Steroids for Topical Use
  7. Drug

    AN0128

    go.drugbank.com/drugs/DB05054
    Investigational

    AN0128 is a good candidate for a topical antibiotic and is currently being developed by Anacor as a novel therapeutic for acne and atopic dermatitis. … The rise in antibiotic resistance of P. acnes to standard antibiotics necessitates the development of new treatment agents.

  8. Drug

    Darusentan

    go.drugbank.com/drugs/DB04883
    Investigational

    It is being evaluated as a treatment for congestive heart failure and hypertension.

  9. Drug

    Sulfachlorpyridazine

    go.drugbank.com/drugs/DB11461
    ExperimentalVet approved

    A sulfonamide antimicrobial used for urinary tract infections and in veterinary medicine.

    Mixtures: TP-KSM 125/625 mg/g Water Soluble Powder
  10. Drug

    Dexetimide

    go.drugbank.com/drugs/DB08997
    ApprovedWithdrawn

    A muscarinic antagonist that has been used to treat neuroleptic-induced parkinsonism. Benzetimide is the (-)-enantimorph of dexetimide.