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Sonpiretigene isteparvovec
go.drugbank.com/drugs/DB17844InvestigationalDeveloped by Nanoscope Therapeutics, it is being investigated for vision restoration in advanced retinitis pigmentosa (RP).
Sodium cation
go.drugbank.com/drugs/DB14516InvestigationalMixtures: PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1000 ML, PERIOLIMEL N4-600E İNFÜZYONLUK ELEKTROLİTLİ AMİNOASİT ÇÖZELTİSİ, GLUKOZ ÇÖZELTİSİ VE LİPİD EMÜLSİYONU, 1500 MLTenecteplase
go.drugbank.com/drugs/DB00031ApprovedInvestigationalTenecteplase is a tissue plasminogen activator (tPA) developed from modifications of natural human tPA complementary DNA (cDNA). It is a 527 amino acid with a substitution of threonine 103 with asparagine and substitution of asparagine 1...
Bexotegrast
go.drugbank.com/drugs/DB16515InvestigationalThe compound was granted orphan drug designation by the US FDA in August 2018 for treatment of IPF, and Pliant Therapeutics recently raised $100 million in Series C financing to support further clinical … PLN-74809 is a small-molecule that dually inhibits both α<sub>v</sub>β<sub>6</sub> and α<sub>v</sub>β<sub>1</sub> to treat both idiopathic pulmonary fibrosis (IPF) and primary sclerosing cholangitis (PSC
Motexafin lutetium
go.drugbank.com/drugs/DB05296InvestigationalIt belongs to the family of drugs called metallotexaphyrins. Also called lutetium texaphyrin. Motexafin lutetium is a pentadentate aromatic metallotexaphyrin with photosensitizing properties.
Santonin
go.drugbank.com/drugs/DB19377ApprovedWithdrawnSantonin is a anthelmintic drug that was previously approved in the US to treat certain parasitic infections.
JSM 6427
go.drugbank.com/drugs/DB06139InvestigationalJSM 6427 is the first small molecule alpha5beta1 integrin receptor antagonist of its kind to be developed.
CRx-401
go.drugbank.com/drugs/DB05775ExperimentalUnlike other NSAIDs, or non-steroidal anti-inflammatory drugs, the dose of diflunisal in CRx-401 has demonstrated in preclinical studies the ability to synergistically enhance the anti-diabetic effects … has proven to be well tolerated in clinical trials.
Clothiapine
go.drugbank.com/drugs/DB13256ApprovedClothiapine has been approved in European countries and is an atypical antipsychotic, shown to be useful in some treatment-resistant patients.