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FET F-18
go.drugbank.com/drugs/DB15405InvestigationalFET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).
Categories: fluoroethyl-L-tyrosine (18F)Synonyms: O-(2-FLUOROETHYL)-L-TYROSINE F-18, O-18F-fluoroethyl-L-tyrosineAcalisib
go.drugbank.com/drugs/DB15407InvestigationalAcalisib is under investigation in clinical trial NCT01705847 (A Phase 1b Study Evaluating GS-9820 in Subjects With Lymphoid Malignancies).
(S)-Propafenone
go.drugbank.com/drugs/DB15410Investigational(S)-Propafenone is under investigation in clinical trial NCT02710669 (New Formulations of Propafenone to Treat Atrial Fibrillation).
Synonyms: (S)-Propafenone, (-)-(S)-PropafenoneCM-4307
go.drugbank.com/drugs/DB15414InvestigationalCM-4307 is under investigation in clinical trial NCT03602495 (Donafenib in 131I-Refractory Differentiated Thyroid Cancer).
Categories: Heterocyclic Compounds, 1-RingTomaralimab
go.drugbank.com/drugs/DB15415InvestigationalTomaralimab is under investigation in clinical trial NCT01794663 (Placebo-Controlled Study to Evaluate the Safety and Efficacy of OPN-305 in Preventing Delayed Renal Graft Function).
Synonyms: Humanized IGG4 monoclonal antibody against toll-like receptor 2 for prevention of ischemia/reperfusion tissue injuryCategories: Immunoglobulin GNanatinostat
go.drugbank.com/drugs/DB15419InvestigationalNanatinostat is under investigation in clinical trial NCT00697879 (Safety Study of the Histone Deacetylase Inhibitor, CHR-3996, in Patients With Advanced Solid Tumours).
Categories: Heterocyclic Compounds, 1-RingArtemin
go.drugbank.com/drugs/DB15438InvestigationalArtemin is under investigation in clinical trial NCT01842126 (Phase 1 Subcutaneous Single and Multiple Ascending Dose Study of BG00010 (Neublastin)).
Navoximod
go.drugbank.com/drugs/DB15439InvestigationalNavoximod is under investigation in clinical trial NCT02048709 (Indoleamine 2,3-Dioxygenase (IDO) Inhibitor in Advanced Solid Tumors).
Categories: Heterocyclic Compounds, 1-Ring, Heterocyclic Compounds, 2-RingElexacaftor
go.drugbank.com/drugs/DB15444ApprovedInvestigational[L9395] Elexacaftor is considered a next-generation CFTR corrector as it possesses both a different structure and mechanism as compared to first generation correctors like tezacaftor. … Elexacaftor (previously VX-445) is a small molecule, next-generation corrector of the cystic fibrosis transmembrane conductance regulator (CFTR) protein.
Categories: P-glycoprotein inhibitors, P-glycoprotein substratesAcumapimod
go.drugbank.com/drugs/DB15448InvestigationalAcumapimod is under investigation in clinical trial NCT02926326 (The Effect of Azithromycin on BCT197 Exposure in Healthy Male Volunteers).
Categories: Heterocyclic Compounds, 1-Ring