Floretyrosine F 18

DB15405InvestigationalSmall molecule

FET F-18 is under investigation in clinical trial NCT01756352 (FET-PET for Evaluation of Response of Recurrent GBM to Avastin).

Chemical structure of Floretyrosine F 18
Mechanism
Curator reviewed
Formula / weight
C11H14FNO3 · 226.238 g/mol (avg)
Also known as
18F-FET · Floretyrosine F18 · FLUOROETHYL-L-TYROSINE (18F) · O-(2-[18F]Fluoroethyl)-L-tyrosine · O-(2-FLUOROETHYL)-L-TYROSINE F-18
Code names
FET F-18

Resolves to

Compound
UNII1326R5J1IACAS178433-03-9ChEMBLCHEMBL477278ChEBI748989PubChem9834479
Clinical / RWD
ATCV09IX10
Structure
InChIKeyQZZYPHBVOQMBAT-LRAGLOQXSA-NSMILESN[C@@H](CC1=CC=C(OCC[18F])C=C1)C(O)=O
Targets
Q01650SLC7A5
Transporters
Q01650SLC7A5

What you can answer from here — as of September 23, 2026

1Protein targetEach mapped to UniProt, with action and pharmacological action
Listed above
1TransporterSubstrate / inhibitor direction, not just membership
Listed above
10Clinical trialsPhase, status and sponsor resolved per trial
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2Structured indicationsCondition, population, route and combination as fields, not prose
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1ATC codeIncluding every combination product, plus 2 drug categories
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7+ReferencesStructured and connected to the statements they support
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Which drugs share a target with Floretyrosine F 18, and which of those have an active Phase 3 trial?

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